SCHEMBL3700532

SCHEMBL3700532

COC(=O)CNC(=O)C(=O)OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 1.00
EGLN1 Q9GZT9 2/20 0.67
RECQL P46063 1/20 0.52
TSHR P16473 5/20 0.43
HSD17B10 Q99714 3/20 0.42
GAA P10253 2/20 0.41
KDM4E B2RXH2 2/20 0.41
EPHX2 P34913 1/20 0.41
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
ALOX5 P09917 1/20 0.39
TGFBR1 P36897 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.36
CA14 Q9ULX7 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2760574 0.84
SCHEMBL22314666 0.82 TET2 (0.69) TET2EGLN1RECQLGAATGFBR1
SCHEMBL18039340 0.82 TET2 (0.69) TET2EGLN1TSHRGAAKDM4E
SCHEMBL1809100 0.82 TET2 (0.69) TET2EGLN1RECQLTSHRHSD17B10
SCHEMBL2138187 0.80 EGLN1 (0.67) TET2EGLN1RECQLTSHRGAA
SCHEMBL18039446 0.80 TET2 (0.67) TET2EGLN1RECQLTSHRHSD17B10
SCHEMBL16133035 0.80 EGLN1 (1.00) TET2EGLN1TSHRKDM4ETGFBR1
SCHEMBL13686153 0.80 TET2 (0.67) TET2EGLN1RECQLTSHRHSD17B10
SCHEMBL29883431 0.79 TET2 (0.62) TET2EGLN1RECQLTSHRHSD17B10
SCHEMBL13684762 0.76 TET2 (0.61) TET2EGLN1RECQLTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107052-A1 COMBINATION TREATMENTS USING EPIGENETIC INHIBITION AND SYNGRI-MEDIATED FRATAXIN EXPRESSION ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2026-05-21 WO claimed
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON UNIV RAMOT (IL) 2026-05-07 US claimed
EP-4712948-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME Renagade Therapeutics Management Inc. (US) 2026-03-25 EP claimed
EP-3947736-B1 PROGNOSIS METHOD OF CANCER CENTRE NAT RECH SCIENT (FR) 2026-03-11 EP claimed
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US claimed
EP-3803568-B1 AGGREGATION OF CONNECTED OBJECTS ORANGE (FR) 2026-01-28 EP claimed
EP-4680243-A1 METHODS FOR TREATMENT OF AGE-RELATED MACULAR DEGENERATION The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2026-01-21 EP claimed
EP-4661861-A1 USE OF HIF-1A STABILIZING AGENTS FOR THE TREATMENT OF TYPE I INTERFERONOPATHIES Institut National de la Santé et de la Recherche Médicale (FR) 2025-12-17 EP claimed
EP-4655288-A1 PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP claimed
WO-2025049959-A9 GENE EDITING SYSTEMS, COMPOSITIONS, AND METHODS FOR TREATMENT OF VEXAS SYNDROME RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-06-12 WO claimed
US-20220347167-A1 A NEW TREATMENT FOR MEIBOMIAN GLAND DYSFUNCTION THE SCHEPENS EYE RESEARCH INSTITUTE, INC. 2022-11-03 US claimed
WO-2022132678-A1 BIOLOGICAL DELIVERY SYSTEMS DNALITE THERAPEUTICS, INC. (US) 2022-06-23 WO claimed
US-20220186321-A1 PROGNOSIS METHOD OF CANCER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-06-16 US claimed
US-11311538-B2 Compositions and methods for targeting cancers YALE UNIVERSITY (US) 2022-04-26 US claimed
EP-3947736-A1 PROGNOSIS METHOD OF CANCER Centre national de la recherche scientifique (FR) 2022-02-09 EP claimed
US-20200397777-A1 PREVENTION AND TREATMENT OF ORGAN FIBROSIS CORNELL UNIVERSITY 2020-12-24 US claimed
EP-3737693-A2 PREVENTION AND TREATMENT OF ORGAN FIBROSIS Cornell University (US) 2020-11-18 EP claimed
CN-111819190-A Prevention and treatment of organ fibrosis 康奈尔大学 2020-10-23 CN claimed
US-20190298709-A1 HIF-STABILIZATION AND PREVENTION OF HYPEROXIA-INDUCED NEONATAL LUNG DISEASE CORNELL UNIVERSITY 2019-10-03 US claimed
WO-2017143131-A1 HIF-STABILIZATION AND PREVENTION OF HYPEROXIA-INDUCED NEONATAL LUNG DISEASE CORNELL UNIVERSITY (US) 2017-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220347167-A1 A NEW TREATMENT FOR MEIBOMIAN GLAND DYSFUNCTION HIF1AN, HIF1A, MTNR1A TET2 2294/4885EGLN1 11/4885RECQL 1614/4885
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON RNMT, TRMT1L, UPF1 TET2 1402/4885EGLN1 3552/4885RECQL 1747/4885
US-20260027096-A1 PHD INHIBITORS HIF1AN, HIF1A, EGLN1 TET2 34/4885EGLN1 3/4885RECQL 4147/4885
US-20190298709-A1 HIF-STABILIZATION AND PREVENTION OF HYPEROXIA-INDUCED NEONATAL LUNG DISEASE HIF1AN, HIF1A, EGLN2 TET2 3136/4885EGLN1 5/4885RECQL 3598/4885
US-20200397777-A1 PREVENTION AND TREATMENT OF ORGAN FIBROSIS MMP1, P4HA1, SERPINH1 TET2 4313/4885EGLN1 1390/4885RECQL 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.