SCHEMBL1809162

SCHEMBL1809162

COC(=O)CSc1c[c]c(F)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
MAPT P10636 3/20 0.43
HSD17B10 Q99714 3/20 0.43
HPGD P15428 3/20 0.43
TP53 P04637 2/20 0.43
KMT2A Q03164 5/20 0.42
POLB P06746 3/20 0.42
RXFP1 Q9HBX9 2/20 0.42
PRNP P04156 1/20 0.42
GLA P06280 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
GAA P10253 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 2/20 0.38
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6597838 0.86 ALDH1A1 (0.43) ALDH1A1MAPTHSD17B10HPGDTP53
SCHEMBL6595260 0.80 MAPT (0.56) ALDH1A1MAPTHSD17B10HPGDTP53
SCHEMBL8599203 0.74 ALDH1A1 (0.43) ALDH1A1MAPTHSD17B10HPGDTP53
SCHEMBL6597414 0.73 ALDH1A1 (0.38) ALDH1A1MAPTHSD17B10HPGDKMT2A
SCHEMBL6593484 0.72 L3MBTL1 (0.37) ALDH1A1MAPTHSD17B10KMT2APOLB
SCHEMBL6592805 0.72 LMNA (0.60) ALDH1A1MAPTHPGDKMT2AKDM4E
SCHEMBL26968170 0.71 ALDH1A1 (0.46) ALDH1A1MAPTHSD17B10HPGDTP53
SCHEMBL8807177 0.70 MAPT (0.50) ALDH1A1MAPTHPGDKMT2APOLB
SCHEMBL4979269 0.70 KMT2A (0.50) ALDH1A1MAPTHSD17B10HPGDTP53
SCHEMBL7689949 0.69 ALDH1A1 (0.39) ALDH1A1MAPTHSD17B10HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107668-B2 HERBICIDES FOR TOLERANT OR RESISTANT SUGAR BEET CULTURES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP disclosed
EP-2319315-B2 Herbicide device for tolerant or resistant maize cultures BAYER CROPSCIENCE AG (DE) 2018-02-21 EP disclosed
EP-2327305-B1 Herbicides for tolerant or resistant soy cultures BAYER CROPSCIENCE AG (DE) 2016-10-26 EP disclosed
EP-2319317-B1 Herbicides for tolerant or resistant cotton cultures BAYER CROPSCIENCE AG (DE) 2016-10-26 EP disclosed
EP-1104242-B2 HERBICIDAL AGENTS FOR TOLERANT OR RESISTANT RICE CROPS BAYER CROPSCIENCE AG (DE) 2016-07-06 EP disclosed
EP-2904902-A1 Herbicides for tolerant or resistant soy cultures Bayer CropScience AG (DE) 2015-08-12 EP disclosed
US-8772199-B2 Herbicidal compositions for tolerant or resistant maize crops BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-08 US disclosed
US-20140121107-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT RICE CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-01 US disclosed
EP-2319316-B1 Herbicide device for tolerant or resistant maize cultures BAYER CROPSCIENCE AG (DE) 2014-02-26 EP disclosed
EP-2319315-B1 Herbicide device for tolerant or resistant maize cultures BAYER CROPSCIENCE AG (DE) 2014-02-26 EP disclosed
US-6162765-A Substituted N-aryl nitrogen-containing heterocyclic compounds BAYER AKTIENGESELLSCHAFT (DE) 2000-12-19 US disclosed
WO-2000008939-A1 HERBICIDES FOR TOLERANT OR RESISTANT SUGAR BEET CULTURES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
WO-2000008938-A1 HERBICIDES FOR TOLERANT OR RESISTANT OIL SEED RAPE CULTURES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
WO-2000008935-A1 HERBICIDAL AGENTS FOR TOLERANT OR RESISTANT RICE CROPS AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
WO-2000008937-A1 HERBICIDES FOR TOLERANT OR RESISTANT COTTON CULTURES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
WO-2000008940-A1 HERBICIDES FOR TOLERANT OR RESISTANT CEREAL CULTURES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
WO-2000008936-A1 HERBICIDES FOR TOLERANT OR RESISTANT CORN CULTURES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
WO-2000008934-A1 HERBICIDAL AGENTS FOR TOLERANT OR RESISTANT SOYBEAN CROPS AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed
EP-0797573-A1 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES BAYER AG (DE) 1997-10-01 EP disclosed
WO-1996018618-A1 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1996-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140121107-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT RICE CROPS PPOX, CYP4X1, GLG1 ALDH1A1 1470/4885MAPT 3111/4885HSD17B10 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.