Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11971363 | 1.00 | HPGD (0.53) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL16621035 | 1.00 | HPGD (0.53) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL2306872 | 0.89 | HTT (0.62) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL2306868 | 0.89 | HTT (0.62) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL11898554 | 0.89 | HTT (0.62) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL10144900 | 0.87 | METAP1 (0.45) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL571311 | 0.87 | METAP1 (0.45) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL571312 | 0.87 | METAP1 (0.45) | HPGDL3MBTL1HTTSRD5A1SRD5A2 | |
| SCHEMBL23950429 | 0.86 | L3MBTL1 (0.53) | HPGDL3MBTL1HTTMAPTMEN1 | |
| SCHEMBL15956234 | 0.86 | L3MBTL1 (0.53) | HPGDL3MBTL1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | BEIGENE SWITZERLAND GMBH (CH) | 2025-05-15 | — | — | US | disclosed |
| US-12185626-B2 | Chemical compounds, optoelectronic elements comprising at least one new chemical compound, and use of new chemical compounds in an optoelectronic element | HELIATEK GMBH (DE) | 2024-12-31 | — | — | US | disclosed |
| EP-3890041-B1 | NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT | HELIATEK GMBH (DE) | 2024-12-04 | — | — | EP | disclosed |
| EP-4448513-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BeiGene Switzerland GmbH (CH) | 2024-10-23 | — | — | EP | disclosed |
| US-20240254110-A1 | FUSED 1,4-DIHYDRODIOXIN DERIVATIVES AS INHIBITORS OF HEAT SHOCK TRANSCRIPTION FACTOR 1 | CANCER RESEARCH TECH LTD (GB) | 2024-08-01 | — | — | US | disclosed |
| CN-118401514-A | 3, 4-Dihydroisoquinolin-1 (2H) -one derivatives as STING antagonists and uses thereof | 百济神州有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-117946138-A | And ring nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-11787786-B2 | Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1 | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-10-17 | — | — | US | disclosed |
| WO-2023109912-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-22 | — | — | WO | disclosed |
| US-20230165146-A1 | CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT | HELIATEK GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20160159774-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2016-06-09 | — | — | US | disclosed |
| US-20160157491-A1 | Pesticide Compounds | BASF SE (DE) | 2016-06-09 | — | — | US | disclosed |
| EP-3022185-A1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2016-05-25 | — | — | EP | disclosed |
| US-9216972-B2 | Tricyclic heterocyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-12-22 | — | — | US | disclosed |
| WO-2015049535-A1 | FUSED 1,4-DIHYDRODIOXIN DERIVATIVES AS INHIBITORS OF HEAT SHOCK TRANSCRIPTION FACTOR 1 | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015007682-A1 | PESTICIDE COMPOUNDS | BASF SE (DE) | 2015-01-22 | — | — | WO | disclosed |
| EP-2592071-A1 | Tricyclic heterocyclic compounds | Bristol-Myers Squibb Company (US) | 2013-05-15 | — | — | EP | disclosed |
| EP-2493866-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS | Bristol-Myers Squibb Company (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120214767-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2012-08-23 | — | — | US | disclosed |
| WO-2011059784-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160157491-A1 | Pesticide Compounds | C1R, C1S, CBR3 | HPGD 4430/4885L3MBTL1 705/4885HTT 1002/4885 |
| US-20120214767-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS | S1PR1, S1PR3, TBXA2R | HPGD 957/4885L3MBTL1 4429/4885HTT 3837/4885 |
| US-20230165146-A1 | CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT | ETV6, ALK, CHRM3 | HPGD 4655/4885L3MBTL1 1636/4885HTT 2009/4885 |
| US-20240254110-A1 | FUSED 1,4-DIHYDRODIOXIN DERIVATIVES AS INHIBITORS OF HEAT SHOCK TRANSCRIPTION FACTOR 1 | HSF1, HSP90AB1, HSPB1 | HPGD 197/4885L3MBTL1 1986/4885HTT 528/4885 |
| US-20160159774-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | HPGD 1580/4885L3MBTL1 3899/4885HTT 89/4885 |
| US-11787786-B2 | Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1 | HSF1, HSP90AB1, HSPB1 | HPGD 197/4885L3MBTL1 1986/4885HTT 528/4885 |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | STING1, IRF3, MAVS | HPGD 1514/4885L3MBTL1 2338/4885HTT 4338/4885 |
| US-12185626-B2 | Chemical compounds, optoelectronic elements comprising at least one new chemical compound, and use of new chemical compounds in an optoelectronic element | ETV6, ALK, CHRM3 | HPGD 4655/4885L3MBTL1 1636/4885HTT 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.