Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 6/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306868 | 1.00 | HTT (0.62) | HTTSRD5A1SRD5A2LMNAHSD17B10 | |
| SCHEMBL2306872 | 1.00 | HTT (0.62) | HTTSRD5A1SRD5A2LMNAHSD17B10 | |
| SCHEMBL1809334 | 0.89 | HPGD (0.53) | HTTSRD5A1SRD5A2PARP10PARP11 | |
| SCHEMBL16621035 | 0.89 | HPGD (0.53) | HTTSRD5A1SRD5A2PARP10PARP11 | |
| SCHEMBL11971363 | 0.89 | HPGD (0.53) | HTTSRD5A1SRD5A2PARP10PARP11 | |
| SCHEMBL595554 | 0.85 | HTT (0.49) | HTTSRD5A1SRD5A2LMNAHSD17B10 | |
| SCHEMBL595553 | 0.85 | HTT (0.49) | HTTSRD5A1SRD5A2LMNAHSD17B10 | |
| SCHEMBL595555 | 0.85 | HTT (0.49) | HTTSRD5A1SRD5A2LMNAHSD17B10 | |
| SCHEMBL204100 | 0.79 | SRD5A1 (0.64) | SRD5A1SRD5A2PARP10PARP11L3MBTL1 | |
| SCHEMBL31268305 | 0.79 | SRD5A1 (0.64) | SRD5A1SRD5A2PARP10PARP11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180002346-A1 | AZOLOBENZAZINE COMPOUNDS, COMPOSITIONS COMPRISING THESE COMPOUNDS AND THEIR USE FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2018-01-04 | — | — | US | disclosed |
| US-9809553-B2 | Isoquinoline compounds, a process for their preparation, and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2017-11-07 | — | — | US | disclosed |
| US-20170137385-A1 | ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2017-05-18 | — | — | US | disclosed |
| US-9497970-B2 | Pesticide compounds | BASF SE (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20160157491-A1 | Pesticide Compounds | BASF SE (DE) | 2016-06-09 | — | — | US | disclosed |
| US-8633237-B2 | Indane derivatives | MERCK SHARP & DOHME B.V. (NL) | 2014-01-21 | — | — | US | disclosed |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20120202781-A1 | INDANE DERIVATIVES | MSD OSS B.V. (NL) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160157491-A1 | Pesticide Compounds | C1R, C1S, CBR3 | HTT 1002/4885SRD5A1 1472/4885SRD5A2 1757/4885 |
| US-20180002346-A1 | AZOLOBENZAZINE COMPOUNDS, COMPOSITIONS COMPRISING THESE COMPOUNDS AND THEIR USE FOR CONTROLLING INVERTEBRATE PESTS | DDT, CRY1, TH | HTT 1809/4885SRD5A1 2561/4885SRD5A2 2333/4885 |
| US-20170137385-A1 | ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MYLK, MYLK2, MYLK3 | HTT 3543/4885SRD5A1 3199/4885SRD5A2 3288/4885 |
| US-20120202781-A1 | INDANE DERIVATIVES | CHRNA5, CHRNA2, GRIK5 | HTT 1124/4885SRD5A1 1148/4885SRD5A2 1305/4885 |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | NOS2, PDXK, GSTK1 | HTT 2472/4885SRD5A1 1444/4885SRD5A2 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.