SCHEMBL18093452

SCHEMBL18093452

Cc1cc(Cl)nc(C(C#N)c2cc(C)cc(Cl)n2)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
GAA P10253 5/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 4/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
POLB P06746 1/20 0.31
MAPT P10636 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
HTT P42858 1/20 0.30
KCNH2 Q12809 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15980614 0.75 NOS3 (0.57) ALDH1A1LMNANOS3NOS1NOS2
SCHEMBL165100 0.71
SCHEMBL1162976 0.69 KDM4E (0.38) ALDH1A1L3MBTL1LMNAMAPTTDP1
SCHEMBL31703186 0.69 KDM4E (0.38) ALDH1A1L3MBTL1LMNAMAPTTDP1
SCHEMBL14556439 0.68 L3MBTL1 (0.40) ALDH1A1GAAL3MBTL1LMNAPOLB
SCHEMBL19341243 0.65
SCHEMBL30578987 0.65
SCHEMBL390280 0.65
SCHEMBL19786436 0.64 ALDH1A1 (0.53) ALDH1A1GAAL3MBTL1LMNAMAPT
SCHEMBL11447182 0.61 NOS3 (0.42) ALDH1A1NOS3NOS1NOS2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-10-09 US disclosed
US-20190088888-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-21 US disclosed
US-20190088888-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-21 US disclosed
US-9871214-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-01-16 US disclosed
US-9871214-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-01-16 US disclosed
US-9871214-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-01-16 US disclosed
US-20160285014-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-29 US disclosed
US-20160285014-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-29 US disclosed
US-20160285014-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160285014-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXSR1, OXER1, OXGR1 ALDH1A1 2491/4885GAA 4453/4885L3MBTL1 1842/4885
US-20250313585-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, AP2M1, LAGE3 ALDH1A1 2584/4885GAA 4151/4885L3MBTL1 88/4885
US-20190088888-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, AP2M1, LAGE3 ALDH1A1 2584/4885GAA 4151/4885L3MBTL1 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.