Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MPL | P40238 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805810 | 0.92 | MPL (0.52) | MAPTTP53MPLKCNK3KCNK9 | |
| SCHEMBL18805807 | 0.85 | POLB (0.42) | MAPTTP53MPLADORA3THRB | |
| SCHEMBL18094527 | 0.85 | MAPT (0.51) | MAPTTP53ADORA3MEN1NPC1 | |
| SCHEMBL18094494 | 0.84 | TLR7 (0.54) | MPLADORA3GRM1KDM4AKDM4B | |
| SCHEMBL18094569 | 0.84 | ADORA3 (0.47) | MAPTTP53MPLKCNK3KCNK9 | |
| SCHEMBL18094514 | 0.83 | THRB (0.45) | MAPTMPLADORA3THRBSMN1; SMN2 | |
| SCHEMBL18094554 | 0.83 | ADORA3 (0.51) | MAPTTP53MPLADORA3GRM1 | |
| SCHEMBL18094572 | 0.82 | MAPT (0.53) | MAPTTP53MPLADORA3THRB | |
| SCHEMBL18094560 | 0.81 | MAPT (0.59) | MAPTTP53ADORA3THRBMEN1 | |
| SCHEMBL18378917 | 0.81 | MPL (0.51) | MAPTTP53MPLKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202849-A1 | ANTIPARASITIC COMPOUNDS | AVISTA PHARMA SOLUTIONS, INC. | 2017-07-20 | — | — | US | claimed |
| US-9643963-B2 | Antiparasitic compounds | AVISTA PHARMA SOLUTIONS, INC. (US) | 2017-05-09 | — | — | US | claimed |
| US-20160280700-A1 | ANTIPARASITIC COMPOUNDS | SNAPDRAGON CHEMISTRY, INC. | 2016-09-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280700-A1 | ANTIPARASITIC COMPOUNDS | TPP2, TPP1, SERPINB1 | MAPT 2921/4885TP53 4794/4885MPL 598/4885 |
| US-20170202849-A1 | ANTIPARASITIC COMPOUNDS | TPP2, TPP1, SERPINB1 | MAPT 2921/4885TP53 4794/4885MPL 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.