Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12625738 | 0.90 | CYP11B1 (0.41) | ERN1AKR1C3AKR1C2PTGS2APP | |
| SCHEMBL10021838 | 0.89 | ALOX5AP (0.38) | ERN1AKR1C3AKR1C2PTGS2APP | |
| SCHEMBL12357204 | 0.88 | GPR3 (0.40) | ERN1AKR1C3AKR1C2PTGS2APP | |
| SCHEMBL17407700 | 0.87 | ALOX5AP (0.39) | ERN1ALOX5APFEN1FFAR1FFAR4 | |
| SCHEMBL9913188 | 0.86 | ALOX5AP (0.38) | ERN1ALOX5APFEN1FFAR1FFAR4 | |
| SCHEMBL19557566 | 0.86 | ALOX5AP (0.38) | ERN1ALOX5APFEN1CD274FFAR1 | |
| SCHEMBL20380717 | 0.85 | ALOX5AP (0.36) | ERN1AKR1C3AKR1C2ALOX5APFEN1 | |
| SCHEMBL14767335 | 0.85 | ALOX5AP (0.39) | ERN1PTGS2APPCYP2C19ALOX5AP | |
| SCHEMBL15374870 | 0.85 | ALOX5AP (0.39) | ERN1PTGS2APPCYP2C19ALOX5AP | |
| SCHEMBL12624690 | 0.85 | ALOX5AP (0.39) | ERN1PTGS2APPCYP2C19ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657230-B2 | Alkenyl dioxane compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | YBX1, PIEZO1, HAX1 | ERN1 970/4885AKR1C3 611/4885AKR1C2 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.