SCHEMBL181016

SCHEMBL181016

CCO[Si](OCC)(OCC)c1ccc(CCl)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733889 0.93 TTR (0.35)
SCHEMBL1223710 0.86 AKT1 (0.33)
SCHEMBL20478197 0.84 NQO1 (0.35)
SCHEMBL50701 0.84 NQO1 (0.35)
SCHEMBL3687475 0.84 CSNK2A1 (0.31) CA1CA2
SCHEMBL3482503 0.83 TP53 (0.39) CA2
SCHEMBL3458351 0.83 TAAR1 (0.33)
SCHEMBL2947258 0.81 THRA (0.33) CA1CA2
SCHEMBL18037942 0.81
SCHEMBL544789 0.80 NQO1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878826-A Preparation method of reactive temperature-resistant hyperbranched organic silicon resin containing chlorinated hydrocarbon groups 南京大学 2024-11-01 CN claimed
CN-116355253-A Preparation method and application of hybrid co-crosslinking type polyphenyl ether/carbon nanotube anion exchange membrane 常州大学 2023-06-30 CN claimed
EP-3055359-B1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2023-06-07 EP claimed
EP-3055361-B1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2023-06-07 EP claimed
EP-3055360-B1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2021-06-23 EP claimed
EP-3055362-B1 TREATED FILLERS COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2021-04-21 EP claimed
US-10882927-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2021-01-05 US claimed
US-10882928-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2021-01-05 US claimed
CN-105764999-B Treated fillers, compositions containing the same, and articles prepared therefrom PPG工业俄亥俄公司 2020-07-07 CN claimed
CN-106062088-B Processed filler, the composition comprising the filler and the product prepared by the filler PPG工业俄亥俄公司 2018-12-07 CN claimed
WO-2015054107-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2015-04-16 WO claimed
US-20150099825-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom QEMETICA S.A. (PL) 2015-04-09 US claimed
US-20150099826-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom PPG INDUSTRIES OHIO, INC. 2015-04-09 US claimed
US-20150099824-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom PPG INDUSTRIES OHIO, INC. 2015-04-09 US claimed
US-8846806-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2014-09-30 US claimed
CN-103890105-A TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC 2014-06-25 CN claimed
US-20130079445-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM QEMETICA S.A. (PL) 2013-03-28 US claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 CA1 1043/4885CA2 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.