SCHEMBL19085533

SCHEMBL19085533

C=C/C=C(\N=C/C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 1/20 0.36
▸ ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18792258 0.82 AKT1 (0.38) AKT1
SCHEMBL18792399 0.81 ATM (0.37) AKT1ATM
SCHEMBL26482446 0.81 TSHR (0.32) ATM
SCHEMBL18105408 0.76 KMT2A (0.35) AKT1ATM
SCHEMBL25107060 0.76 MEN1 (0.35) AKT1ATM
SCHEMBL20697741 0.75 KDM4E (0.43) —
SCHEMBL19085444 0.74 AKT1 (0.38) AKT1ATM
SCHEMBL26535603 0.73 GPR3 (0.38) —
SCHEMBL25113036 0.71 AKT1 (0.37) AKT1ATM
SCHEMBL12177014 0.70 ESR1 (0.35) AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 — — US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 — — US disclosed
US-10892426-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-12 — — US disclosed
US-20200152890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-14 — — US disclosed
US-10593896-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-17 — — US disclosed
US-10454041-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-10-22 — — US disclosed
US-20190148651-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-16 — — US disclosed
US-10186672-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-01-22 — — US disclosed
US-20170194577-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454041-B2 Materials for organic electroluminescent devices RIF1, INTS9, LEF1 AKT1 4235/4885ATM 3972/4885
US-20200152890-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, LMNB2, RUVBL2 AKT1 4093/4885ATM 2983/4885
US-10892426-B2 Organic electroluminescent materials and devices OCIAD2, LMNB2, RUVBL2 AKT1 4093/4885ATM 2983/4885
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, MCM4, KCNMB4 AKT1 3344/4885ATM 4022/4885
US-20190148651-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, DDT, EML4 AKT1 4249/4885ATM 4242/4885
US-10593896-B2 Organic electroluminescent materials and devices TYR, DDT, EML4 AKT1 4249/4885ATM 4242/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM AKT1 3128/4885ATM 3636/4885
US-10186672-B2 Organic electroluminescent materials and devices TYR, DDT, EML4 AKT1 4249/4885ATM 4242/4885
US-20170194577-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, DDT, EML4 AKT1 4249/4885ATM 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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