Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18792399 | 0.81 | ATM (0.37) | TSHRKDM4EMAPTPOLBATM | |
| SCHEMBL19101609 | 0.81 | TSHR (0.32) | TSHRKDM4EMAPTPOLBATM | |
| SCHEMBL19085533 | 0.81 | AKT1 (0.36) | ATM | |
| SCHEMBL18937464 | 0.74 | ATM (0.32) | TSHRMAPTPOLBATMCYP3A4 | |
| SCHEMBL15152900 | 0.73 | ALDH1A1 (0.38) | TSHRMAPTPOLBCYP3A4TDP1 | |
| SCHEMBL9519534 | 0.73 | ALDH1A1 (0.38) | TSHRMAPTPOLBCYP3A4TDP1 | |
| SCHEMBL9519520 | 0.73 | ALDH1A1 (0.38) | TSHRMAPTPOLBCYP3A4TDP1 | |
| SCHEMBL25107060 | 0.72 | MEN1 (0.35) | MAPTATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18105408 | 0.72 | KMT2A (0.35) | KDM4EMAPTPOLBATML3MBTL1 | |
| SCHEMBL11349870 | 0.71 | KDM1A (0.41) | TSHRMAPTPOLBCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643414-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643414-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, PIEZO1 | TSHR 4722/4885KDM4E 2933/4885MAPT 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.