Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 10/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37829 | 0.85 | SLC5A2 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL180996 | 0.84 | SLC5A1 (0.46) | SLC5A2SLC5A1MAOBFPR1FPR2 | |
| SCHEMBL15397883 | 0.84 | HTR2A (0.42) | SLC5A2SLC5A1 | |
| SCHEMBL15748708 | 0.82 | PKM (0.47) | SLC5A2SLC5A1KMT2AMEN1HTT | |
| SCHEMBL1009096 | 0.80 | MAOB (0.51) | MAOBAPP | |
| SCHEMBL1010022 | 0.77 | ALDH1A1 (0.44) | SLC5A2SLC5A1MAOBKMT2AMEN1 | |
| SCHEMBL1457143 | 0.77 | SLC5A2 (0.35) | SLC5A2SLC5A1MAOBARMAOA | |
| SCHEMBL37695 | 0.76 | KDM4E (0.44) | SLC5A2SLC5A1 | |
| SCHEMBL25986811 | 0.75 | LTA4H (0.50) | APPHTTL3MBTL1 | |
| SCHEMBL590310 | 0.75 | ALDH1A1 (0.44) | MAOBAPPKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |