SCHEMBL1811071

SCHEMBL1811071

Cc1cc(C(=O)Cl)cc(C)c1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
TDP1 Q9NUW8 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
TSHR P16473 6/20 0.46
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1812368 0.82 MAPK1 (0.48) ALDH1A1TDP1KMT2AKDM4EPOLB
SCHEMBL347935 0.82 TSHR (0.59) ALDH1A1TDP1KMT2AKDM4EPOLB
SCHEMBL1813258 0.80 ALDH1A1 (0.47) ALDH1A1TDP1KMT2AKDM4EPOLB
SCHEMBL6455620 0.80 SMN1; SMN2 (0.57) ALDH1A1TDP1KMT2AKDM4EPOLB
SCHEMBL28155919 0.78 TSHR (0.47) ALDH1A1TDP1POLBTSHRCES2
Hydrazine SCHEMBL8178152 0.78 ALDH1A1 (0.36) ALDH1A1TDP1KMT2AKDM4EPOLB
SCHEMBL12383064 0.78 ALDH1A1 (0.48) ALDH1A1TDP1KMT2ATSHRCES2
SCHEMBL3329098 0.78 GPR35 (0.48) ALDH1A1TSHR
SCHEMBL6963428 0.77 ALDH1A1 (0.50) ALDH1A1TDP1KMT2AKDM4EPOLB
SCHEMBL15262672 0.77 ALDH1A1 (0.55) ALDH1A1TDP1KMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240803-B2 Diamine compound, and polyimide precursor and polyimide film using same LG CHEM, LTD. (KR) 2025-03-04 US disclosed
CN-113166046-B Diamine compound, polyimide precursor using same, and polyimide film 株式会社LG化学 2023-06-06 CN disclosed
US-20220017461-A1 DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME LG CHEM, LTD. (KR) 2022-01-20 US disclosed
CN-113166046-A Diamine compound, and polyimide precursor and polyimide film using same 株式会社LG化学 2021-07-23 CN disclosed
CN-102177135-A Acylaminobenzamide derivatives BAYER CROPSCIENCE AG 2011-09-07 CN disclosed
US-20110201603-A1 Novel Acylaminobenzamide Derivatives BAYER CROPSCIENCE AG (DE) 2011-08-18 US disclosed
EP-2318358-A2 ACYLAMINOBENZAMIDE DERIVATIVES Bayer CropScience AG (DE) 2011-05-11 EP disclosed
WO-2010015355-A2 NOVEL ACYLAMINOBENZAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-02-11 WO disclosed
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed
EP-0211568-B1 ANTICONVULSANT AGENTS ELI LILLY AND COMPANY (US) 1989-10-11 EP disclosed
US-4684748-A BENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1987-08-04 US disclosed
EP-0211568-A1 Anticonvulsant agents ELI LILLY AND COMPANY (US) 1987-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240803-B2 Diamine compound, and polyimide precursor and polyimide film using same SRM, PCNA, PUF60 ALDH1A1 1636/4885TDP1 1747/4885KMT2A 347/4885
US-20220017461-A1 DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME SRM, PCNA, PUF60 ALDH1A1 1636/4885TDP1 1747/4885KMT2A 347/4885
US-20110201603-A1 Novel Acylaminobenzamide Derivatives KCNB1, KCNA5, KCNA7 ALDH1A1 271/4885TDP1 3523/4885KMT2A 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.