SCHEMBL18112552

SCHEMBL18112552

C=CC(=O)Oc1[c]c2ccccc2cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
EGFR P00533 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
JAK1 P23458 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
THRB P10828 4/20 0.35
THRA P10827 1/20 0.35
AKT1 P31749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3246397 0.79 KDM4E (0.37) MAPTKMT2ATDP1KDM4EALDH1A1
SCHEMBL28898619 0.77 THRB (0.33) THRBTHRA
SCHEMBL3237917 0.72 CA1 (0.30)
SCHEMBL8533924 0.72
SCHEMBL20524986 0.72 CYP2A6 (0.32) TDP1ALDH1A1ALOX12HSD17B10
SCHEMBL5888944 0.71 HPGD (0.39) MAPTCYP3A4HPGDMAPK1HSD17B10
SCHEMBL24465 0.70 THRB (0.38) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL29456947 0.69 KMT2A (0.59) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL12245559 0.69 KDM4E (0.52) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL31476921 0.69 KMT2A (0.59) MEN1MAPTKMT2ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021132327-A1 TETRAAZAPORPHYRIN COMPOUND, INK COMPOSITION, FILM, OPTICAL MATERIAL, OPTICAL FILM, DISPLAY SURFACE FILM, AND DISPLAY DEVICE 大日本印刷株式会社 2021-07-01 WO disclosed
US-10054855-B2 Chemically amplified positive-type photosensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2018-08-21 US disclosed
US-20160291469-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2016-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10054855-B2 Chemically amplified positive-type photosensitive resin composition POLL, POLR1A, ASIC1 MEN1 1566/4885MAPT 1817/4885KMT2A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.