SCHEMBL18117435

SCHEMBL18117435

NCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 2/20 0.68
▸ PRSS2 P07478 2/20 0.68
▸ PRSS3 P35030 2/20 0.68
▸ TPSAB1 Q15661 2/20 0.68
▸ F2 P00734 1/20 0.68
▸ PKM P14618 3/20 0.66
▸ FOLH1 Q04609 3/20 0.64
▸ TDP1 Q9NUW8 5/20 0.63
▸ CA12 O43570 2/20 0.58
▸ CA1 P00915 2/20 0.58
▸ CA2 P00918 2/20 0.58
▸ CA9 Q16790 2/20 0.58
▸ MEN1 O00255 1/20 0.57
▸ ABL1 P00519 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ IDE P14735 1/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ RIN1 Q13671 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890035 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL12551869 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL21531161 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL25375533 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL19952819 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL24974563 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL24670280 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL24163378 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL21151130 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2
SCHEMBL13021124 1.00 PRSS1 (0.68) PRSS1PRSS2PRSS3TPSAB1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519384-B1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORP (US) 2026-04-29 — — EP disclosed
WO-2025243001-A1 COVALENT TAG UNIVERSITY OF DUNDEE (GB) 2025-11-27 — — WO disclosed
EP-4615837-A1 USEFUL COMPOUNDS FOR MODULATING INFLAMMATION Flagship Pioneering Innovations VI, LLC (US) 2025-09-17 — — EP disclosed
EP-4519385-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2025-03-12 — — EP disclosed
EP-4519384-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF Promega Corporation (US) 2025-03-12 — — EP disclosed
US-20240191211-A1 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION 2024-06-13 — — US disclosed
WO-2024102901-A1 USEFUL COMPOUNDS FOR MODULATING INFLAMMATION FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-05-16 — — WO disclosed
WO-2023215497-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION (US) 2023-11-09 — — WO disclosed
WO-2023215514-A2 BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING PROMEGA CORPORATION (US) 2023-11-09 — — WO disclosed
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2023-11-09 — — US disclosed
US-20230046947-A1 REACTIVE CONJUGATES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2023-02-16 — — US disclosed
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 — — US disclosed
CN-110596365-B Method and kit for determining cholesterol loading capacity of lipoprotein 希森美康株式会社 2022-11-15 — — CN disclosed
US-11486875-B2 Method for measuring cholesterol uptake capacity of lipoproteins SYSMEX CORPORATION (JP) 2022-11-01 — — US disclosed
EP-4069311-A1 REACTIVE CONJUGATES Debiopharm Research & Manufacturing SA (CH) 2022-10-12 — — EP disclosed
EP-3623811-B1 METHOD FOR MEASURING CHOLESTEROL UPTAKE CAPACITY OF LIPOPROTEINS SYSMEX CORP (JP) 2022-07-13 — — EP disclosed
US-20210379044-A1 NON PEPTIDIC HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED 2021-12-09 — — US disclosed
US-20190336489-A1 NON PEPTIDE HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES GLAXOSMITHKLINE IP DEV LTD (GB) 2019-11-07 — — US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 — — WO disclosed
EP-3076175-A1 DETECTION AND QUANTIFICATION OF O-ACETYL-ADP-RIBOSE AS A READOUT SYSTEM FOR MEASURING THE ACTIVITY OF E.G. SIRTUINS Boehringer Ingelheim International GmbH (DE) 2016-10-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357266-A1 PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF BTD, HLCS, TYR PRSS1 3477/4885PRSS2 3699/4885PRSS3 3560/4885
US-20210379044-A1 NON PEPTIDIC HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES ACKR3, CXCR3, CCL2 PRSS1 1431/4885PRSS2 2036/4885PRSS3 1477/4885
US-20230046947-A1 REACTIVE CONJUGATES FCGR3B, FCGR1A, FCGR2A PRSS1 4208/4885PRSS2 4155/4885PRSS3 3661/4885
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B PRSS1 1694/4885PRSS2 2666/4885PRSS3 2347/4885
US-20190336489-A1 NON PEPTIDE HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES ACKR3, CXCR3, CCL2 PRSS1 1647/4885PRSS2 2229/4885PRSS3 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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