Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.68 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117435 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL12551869 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL21531161 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL25375533 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL19952819 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL24974563 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL24670280 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL24163378 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL21151130 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL13021124 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122675-A1 | PROGRAMMABLE POLYMER DROPLETS AND ASSOCIATED USES | ETH ZURICH (CH) | 2022-06-16 | — | — | WO | disclosed |
| EP-4008427-A1 | PROGRAMMABLE POLYMER DROPLETS AND ASSOCIATED USES | ETH Zurich (CH) | 2022-06-08 | — | — | EP | disclosed |
| US-20220160882-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE, LLC | 2022-05-26 | — | — | US | disclosed |
| US-10976312-B2 | Compositions and methods for capture of cellular targets of bioactive agents | PROMEGA CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2021-03-02 | — | — | US | disclosed |
| US-20200108150-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL BUSINESS LTD (GB) | 2020-04-09 | — | — | US | disclosed |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2020-02-04 | — | — | US | disclosed |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2019-01-08 | — | — | US | disclosed |
| US-20170304460-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE, LLC | 2017-10-26 | — | — | US | disclosed |
| US-20120190579-A1 | Functionalisation of Solid Substrates | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120177894-A1 | FUNCTIONALIZATION OF SP3 HYBRIDIZED CARBON, SILICON AND/OR GERMANIUM SURFACES | UNIVERSITE JOSEPH FOURIER (FR) | 2012-07-12 | — | — | US | disclosed |
| US-20120009566-A1 | LUMINESCENCE ASSAY METHOD | OY ARCTIC PARTNERS AB C/O TIMO LOVGREN (FI) | 2012-01-12 | — | — | US | disclosed |
| US-20100015717-A1 | Mass Tags for Quantitive Analysis | PPD BIOMARKER DISCOVERY SCIENCES LLC (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100015717-A1 | Mass Tags for Quantitive Analysis | PPD BIOMARKER DISCOVERY SCIENCES LLC (US) | 2010-01-21 | — | — | US | disclosed |
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090130665-A1 | POLYMER COMPOSITIONS AND USES THEREOF | MCGILL UNIVERSITY (CA) | 2009-05-21 | — | — | US | disclosed |
| US-20090130665-A1 | POLYMER COMPOSITIONS AND USES THEREOF | MCGILL UNIVERSITY (CA) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174094-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | PRSS1 2739/4885PRSS2 3219/4885PRSS3 2901/4885 |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | PRSS1 2739/4885PRSS2 3219/4885PRSS3 2901/4885 |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | PRSS1 2739/4885PRSS2 3219/4885PRSS3 2901/4885 |
| US-20170304460-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | SHBG, PTMS, VIP | PRSS1 2096/4885PRSS2 1071/4885PRSS3 1506/4885 |
| US-20120190579-A1 | Functionalisation of Solid Substrates | XDH, SPR, DAO | PRSS1 191/4885PRSS2 405/4885PRSS3 366/4885 |
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STUB1, SPR, DBI | PRSS1 1538/4885PRSS2 699/4885PRSS3 871/4885 |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | PRSS1 2739/4885PRSS2 3219/4885PRSS3 2901/4885 |
| US-20220160882-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | ZYX, QPCT, MRPL21 | PRSS1 2590/4885PRSS2 2309/4885PRSS3 1898/4885 |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | PRSS1 2739/4885PRSS2 3219/4885PRSS3 2901/4885 |
| US-20200108150-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | F12, F13A1, F2 | PRSS1 2635/4885PRSS2 3110/4885PRSS3 2797/4885 |
| US-20100015717-A1 | Mass Tags for Quantitive Analysis | PTMS, CHAMP1, TMT1A | PRSS1 2560/4885PRSS2 1853/4885PRSS3 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.