Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17994354 | 0.94 | TSHR (0.41) | UTRNPTPN1CYP2A6CYP1A2TDP1 | |
| SCHEMBL11991034 | 0.86 | PTPN1 (0.49) | UTRNPTPN1CYP2A6CYP1A2TDP1 | |
| SCHEMBL11991025 | 0.82 | PTPN1 (0.45) | UTRNPTPN1GSTP1ESR1LMNA | |
| SCHEMBL20900601 | 0.80 | MRGPRX4 (0.34) | UTRNPTPN1LMNANPC1RAB9A | |
| SCHEMBL11991713 | 0.77 | PTPN1 (0.47) | PTPN1CYP2A6CYP1A2GSTP1ESR1 | |
| SCHEMBL13417802 | 0.77 | CYP2A6 (0.44) | PTPN1CYP2A6CYP1A2TDP1GSTP1 | |
| SCHEMBL18085206 | 0.77 | ESR1 (0.48) | PTPN1CYP2A6CYP1A2TDP1GSTP1 | |
| SCHEMBL3833758 | 0.76 | GPR84 (0.45) | PTPN1CYP2A6CYP1A2TDP1GSTP1 | |
| SCHEMBL19735278 | 0.74 | PTPN1 (0.45) | PTPN1CYP2A6TDP1L3MBTL1NPC1 | |
| SCHEMBL14339274 | 0.74 | GPR84 (0.44) | PTPN1CYP2A6CYP1A2TDP1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. | 2021-08-03 | — | — | US | disclosed |
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | LG CHEM, LTD. | 2021-04-06 | — | — | US | disclosed |
| US-20180175304-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-06-21 | — | — | US | disclosed |
| US-20180175304-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-06-21 | — | — | US | disclosed |
| US-9960357-B2 | Spiro-type compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2018-05-01 | — | — | US | disclosed |
| US-9960357-B2 | Spiro-type compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2018-05-01 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2017-12-21 | — | — | US | disclosed |
| US-9502669-B2 | Organic light emitting diode | LG CHEM, LTD. (KR) | 2016-11-22 | — | — | US | disclosed |
| US-20160293852-A1 | ORGANIC LIGHT EMITTING DIODE | LG CHEM, LTD. (KR) | 2016-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180175304-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | UTRN 2978/4885PTPN1 2128/4885CYP2A6 384/4885 |
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | RER1, NR2E3, RIF1 | UTRN 4511/4885PTPN1 692/4885CYP2A6 1317/4885 |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | UTRN 2978/4885PTPN1 2128/4885CYP2A6 384/4885 |
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | ESR1, OR10J3, ERG | UTRN 3091/4885PTPN1 1253/4885CYP2A6 324/4885 |
| US-20170365787-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | CRY1, NR2E3, LEF1 | UTRN 3915/4885PTPN1 1699/4885CYP2A6 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.