SCHEMBL18124398

SCHEMBL18124398

C[Hf](C)C1C=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041345 0.90 KIF11 (0.38) RXRARXRB
SCHEMBL28041264 0.87 BRD4 (0.34)
Hydrochloric Acid SCHEMBL17387042 0.84 RXRA (0.33) RXRARXRB
Hydrochloric Acid SCHEMBL17387003 0.82 HTR1A (0.31)
SCHEMBL17386730 0.80 RXRA (0.34) RXRARXRB
SCHEMBL5859294 0.80 RXRA (0.34) RXRARXRB
SCHEMBL29773672 0.80 RXRA (0.34) RXRARXRB
SCHEMBL29767633 0.80 RXRA (0.34) RXRARXRB
SCHEMBL27978443 0.79 CHRNB2 (0.33)
Hydrochloric Acid SCHEMBL29773667 0.79 RXRA (0.33) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026408-B Metallocene compound, olefin polymer catalyst, the manufacturing method of olefin polymer and olefin polymer 日本聚乙烯株式会社 2018-09-11 CN disclosed
EP-3078670-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER Japan Polyethylene Corporation (JP) 2016-10-12 EP disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed