SCHEMBL28041264

SCHEMBL28041264

C[Hf](C)C1C=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KIF11 P52732 2/20 0.31
S1PR1 P21453 1/20 0.31
DGAT1 O75907 1/20 0.31
PARP1 P09874 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
TNF P01375 1/20 0.30
NOD1 Q9Y239 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18124398 0.87 RXRA (0.33)
SCHEMBL28041345 0.86 KIF11 (0.38) KIF11
SCHEMBL28041360 0.84 EDNRB (0.32) BRD4CREBBP
SCHEMBL27978443 0.83 CHRNB2 (0.33) BRD4
SCHEMBL28041134 0.80
SCHEMBL28041170 0.80 HRH3 (0.36) NPC1TP53SMN1; SMN2
SCHEMBL28041213 0.80 BRD4 (0.34) BRD4CREBBPLMNARAB9A
Hydrochloric Acid SCHEMBL7863578 0.78 KIF11 (0.35) BRD4CREBBPNPC1LMNATP53
Hydrochloric Acid SCHEMBL7863570 0.78 BRD4 (0.34) BRD4CREBBPNPC1LMNATP53
SCHEMBL28238717 0.77 CNR1 (0.32) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026408-B Metallocene compound, olefin polymer catalyst, the manufacturing method of olefin polymer and olefin polymer 日本聚乙烯株式会社 2018-09-11 CN disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed