Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546439 | 0.91 | NPSR1 (0.53) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL29603301 | 0.91 | NPSR1 (0.53) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9798371 | 0.87 | LTA4H (0.54) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL3553556 | 0.86 | LTA4H (0.52) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL27579381 | 0.83 | LTA4H (0.59) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL28909069 | 0.82 | TLR8 (0.48) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9546526 | 0.81 | L3MBTL1 (0.55) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL21820019 | 0.80 | SMN1; SMN2 (0.48) | LTA4HALDH1A1MAPTABCG2TSHR | |
| SCHEMBL1417678 | 0.79 | THRA (0.52) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL4453344 | 0.79 | LMNA (0.54) | TEAD1L3MBTL1NPSR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426473-B2 | Phenoxy acetic acids as PPAR delta activators | High Point Pharnaceuticals, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-8217086-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| EP-1899302-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-07-28 | — | — | US | disclosed |
| US-7943669-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | TRANSTECH PHARMA, INC. (NC) | 2009-07-30 | — | — | US | disclosed |
| EP-1899302-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | Novo Nordisk A/S (DK) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003581-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | PPARA, PPARG, PPARD | TEAD1 818/4885L3MBTL1 4834/4885NPSR1 1795/4885 |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | TEAD1 818/4885L3MBTL1 4834/4885NPSR1 1795/4885 |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | TEAD1 818/4885L3MBTL1 4834/4885NPSR1 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.