SCHEMBL1813993

SCHEMBL1813993

CC(C)N1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.40
USP2 O75604 1/20 0.37
UCHL1 P09936 1/20 0.35
UCHL3 P15374 1/20 0.35
ECE1 P42892 1/20 0.35
MUS81 Q96NY9 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
CA9 Q16790 4/20 0.34
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA7 P43166 3/20 0.33
GAPDH P04406 1/20 0.33
NR1H2 P55055 2/20 0.32
DUSP3 P51452 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
NR1H3 Q13133 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11004743 0.81 KMT2A (0.41) KMT2AUCHL1UCHL3ECE1MUS81
SCHEMBL7564210 0.76 BLM (0.37) KMT2AUSP2ALDH1A1TSHR
SCHEMBL10434439 0.74 CSNK2A2 (0.42) KMT2ACA9CA12CA1CA2
SCHEMBL1815113 0.70 UCHL1 (0.39) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL13784314 0.70 USP2 (0.41) USP2CSNK2A2CSNK2BCSNK2A1
SCHEMBL10935467 0.70 USP2 (0.37) USP2TSHRCA9CA12CA1
SCHEMBL1814738 0.70 CA9 (0.40) KMT2AUCHL1UCHL3ECE1MUS81
SCHEMBL1814110 0.69 UCHL1 (0.43) UCHL1UCHL3ECE1MUS81ALDH1A1
SCHEMBL14175179 0.69 KMT2A (0.36) KMT2ACA9CA12CA1GAPDH
SCHEMBL12370990 0.68 USP2 (0.33) USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022167637-A1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS Technische Universität Berlin (DE) 2022-08-11 WO disclosed
WO-2020252457-A1 PROCESSES AND COMPOUNDS FOR THE DECARBOXYLATIVE AMINATION OF REDOX-ACTIVE ESTERS WITH DIAZIRINES H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2020-12-17 WO disclosed
US-10472315-B2 Inhibitors of methionine aminopeptidases and methods of treating disorders THE JOHNS HOPKINS UNIVERSITY (US) 2019-11-12 US disclosed
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
CN-102666695-B For extruding the polycarbonate compositions of the anti-flammability with improvement of application 科思创德国股份有限公司 2016-08-17 CN disclosed
EP-2496639-B1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER IP GMBH (DE) 2013-12-25 EP disclosed
US-20120244359-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
EP-2496639-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
US-5326800-A Use of salts in combination with halogenated phthalimides for flameproof finishing of glass fibre-containing polycarbonate moulded members BAYER AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
EP-0561238-A2 Use of salts in combination with halogenated phthalimides for flame protection of polycarbonates containing glass fibres BAYER AG (DE) 1993-09-22 EP disclosed
US-4769493-A Process for producing tetrafluorophthalic acid SDS BIOTECH K.K. (JP) 1988-09-06 US disclosed
EP-0259663-A1 Process for producing tetrafluorophihalic acid SDS Biotech K.K. (JP) 1988-03-16 EP disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
EP-0042561-B1 FIRE-PROOFED MOULDING MASSES BASED ON AROMATIC THERMOPLASTIC POLYESTERS, PROCESS FOR ITS PREPARATION AND USE IN THE PRODUCTION OF SHAPED ARTICLES BAYER AG (DE) 1985-03-27 EP disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10472315-B2 Inhibitors of methionine aminopeptidases and methods of treating disorders METAP1, METAP2, ENPEP KMT2A 1373/4885USP2 1868/4885UCHL1 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.