Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | SCD5 | Q86SK9 | 6/20 | 0.56 |
| ▸ | SCD | O00767 | 3/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542566 | 0.85 | ROCK2 (0.62) | ROCK2HSD17B10PARP14PARP10SCD5 | |
| SCHEMBL7729871 | 0.82 | TSHR (0.66) | ROCK2HSD17B10PARP14PARP10SCD5 | |
| SCHEMBL168416 | 0.81 | RIPK1 (0.53) | ROCK2HSD17B10PARP14PARP10SCD5 | |
| SCHEMBL166794 | 0.80 | ROCK2 (0.60) | ROCK2PARP14PARP10SCD5SCD | |
| SCHEMBL166963 | 0.80 | RIPK1 (0.54) | ROCK2PARP14PARP10SCD5SCD | |
| SCHEMBL256556 | 0.79 | RIPK1 (0.53) | ROCK2PARP14PARP10SCD5SCD | |
| SCHEMBL8596155 | 0.78 | PARP14 (0.62) | ROCK2PARP14PARP10SCD5SCD | |
| SCHEMBL164387 | 0.77 | PARP14 (0.60) | ROCK2PARP14PARP10SCD5SCD | |
| SCHEMBL10002512 | 0.76 | RIPK1 (0.64) | HSD17B10SCD5SCDRIPK1HSP90AA1 | |
| SCHEMBL13257687 | 0.76 | TACR1 (0.47) | ROCK2KMT2AL3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770435-B2 | Compounds, pharmaceutical composition and methods for use in treating inflammatory diseases | OGEDA SA (BE) | 2017-09-26 | — | — | US | disclosed |
| US-20160303075-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES | EPICS THERAPEUTICS (BE) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303075-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES | PTGS1, PTGES, PTGER1 | ROCK2 4095/4885HSD17B10 261/4885PARP14 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.