Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.53 |
| ▸ | SCD | O00767 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.49 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729871 | 0.86 | TSHR (0.66) | PARP14PARP10HSD11B1SCD5SCD | |
| SCHEMBL28408689 | 0.85 | ALDH1A1 (0.54) | PARP14PARP10HSP90AA1HSP90AB1HPGD | |
| SCHEMBL16565652 | 0.85 | SCD (0.60) | PARP14PARP10L3MBTL1RIPK1HSP90AA1 | |
| SCHEMBL4019469 | 0.85 | RIPK1 (0.62) | PARP14PARP10RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL27574934 | 0.85 | RIPK1 (0.62) | PARP14PARP10RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL216202 | 0.85 | RIPK1 (0.62) | PARP14PARP10RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL27574946 | 0.85 | RIPK1 (0.62) | PARP14PARP10RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL18286158 | 0.84 | PREP (0.58) | PARP14PARP10RIPK1HSD11B1ROCK2 | |
| SCHEMBL27261597 | 0.84 | PREP (0.55) | PARP14PARP10GAATRPC3TRPC6 | |
| SCHEMBL164387 | 0.84 | PARP14 (0.60) | PARP14PARP10RIPK1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875512-A2 | New naphthylpiperazine derivatives with antipsychotic activity | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1998-11-04 | — | — | EP | disclosed |