Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068671 | 0.80 | MAPT (0.48) | SIRT6CYP3A4LMNATSHRNPSR1 | |
| SCHEMBL1814558 | 0.79 | NOTUM (0.58) | ARSIRT6CYP3A4LMNACYP1A2 | |
| SCHEMBL22353101 | 0.75 | CDK2 (0.40) | CYP1A2KIF11 | |
| SCHEMBL22353117 | 0.74 | ABCC8 (0.46) | ARCYP3A4LMNAALDH1A1ALOX15 | |
| SCHEMBL29074284 | 0.73 | CRHBP (0.49) | ARSIRT6CYP3A4LMNACYP1A2 | |
| SCHEMBL11624085 | 0.73 | KDR (0.46) | ARSIRT6CYP3A4LMNACYP1A2 | |
| SCHEMBL22353092 | 0.73 | AR (0.44) | ARHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17673929 | 0.72 | MAPT (0.56) | CYP3A4LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL28242342 | 0.72 | AR (0.46) | ARHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10939876 | 0.72 | KIF11 (0.51) | ARSIRT6CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161835-B2 | Compounds and their use for reducing uric acid levels | ACQUIST LLC (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200339545-A1 | Compounds And Their Use For Reducing Uric Acid Levels | ACQUIST LLC (US) | 2020-10-29 | — | — | US | disclosed |
| US-10752613-B2 | Compounds and their use for reducing uric acid levels | ACQUIST LLC (US) | 2020-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339545-A1 | Compounds And Their Use For Reducing Uric Acid Levels | XDH, OAT, PON1 | AR 2962/4885HDAC3 3124/4885HDAC1 2606/4885 |
| US-11161835-B2 | Compounds and their use for reducing uric acid levels | XDH, OAT, PON1 | AR 2962/4885HDAC3 3124/4885HDAC1 2606/4885 |
| US-10752613-B2 | Compounds and their use for reducing uric acid levels | XDH, OAT, PON1 | AR 2962/4885HDAC3 3124/4885HDAC1 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.