Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228181 | 0.84 | ALDH1A1 (0.43) | KMT2AMEN1KDM4ETSHRALDH1A1 | |
| SCHEMBL8849128 | 0.83 | POLB (0.38) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL4575872 | 0.76 | KDM4E (0.35) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL1814587 | 0.74 | TAS1R3 (0.52) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL1812603 | 0.73 | SMN1; SMN2 (0.42) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL1720844 | 0.72 | ALDH1A1 (0.38) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL5747695 | 0.72 | TSHR (0.43) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL14405368 | 0.68 | SMN1; SMN2 (0.40) | KMT2AMEN1KDM4ETSHRPOLB | |
| SCHEMBL24841250 | 0.67 | CYP3A4 (0.46) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL1424023 | 0.67 | PTGS1 (0.46) | KDM4ETSHRPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732930-A2 | 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092897-A2 | 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES | BAYER CROPSCIENCE AG (DE) | 2005-10-06 | — | — | WO | disclosed |