Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.39 |
| ▸ | ADK | P55263 | 9/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332561 | 0.80 | PYGL (0.61) | PYGL | |
| SCHEMBL1814865 | 0.80 | PYGL (0.61) | PYGL | |
| SCHEMBL187958 | 0.73 | PYGL (0.35) | PYGL | |
| SCHEMBL7170421 | 0.69 | METAP2 (0.38) | — | |
| SCHEMBL27507094 | 0.67 | KDM4E (0.42) | — | |
| SCHEMBL16631575 | 0.65 | TSHR (0.37) | — | |
| SCHEMBL6538415 | 0.61 | PYGL (0.63) | PYGL | |
| SCHEMBL12899794 | 0.61 | MAPT (0.41) | — | |
| SCHEMBL27452010 | 0.60 | SLC5A2 (0.34) | — | |
| SCHEMBL5446133 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863497-A4 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR PREVENTING OR REDUCING ADVERSE EFFECTS IN A PATIENT | PERICOR THERAPEUTICS INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1863497-A2 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR PREVENTING OR REDUCING ADVERSE EFFECTS IN A PATIENT | Pericor Therapeutics, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006105167-A2 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR PREVENTING OR REDUCING ADVERSE EFFECTS IN A PATIENT | PERICOR THERAPEUTICS, INC. (US) | 2006-10-05 | — | — | WO | disclosed |