Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702768 | 0.73 | GPR35 (0.44) | MEN1KMT2ANQO2GRIN1GRIN2B | |
| SCHEMBL18152815 | 0.72 | HPGD (0.36) | POLBMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL27917903 | 0.72 | CCNB2 (0.36) | HPGDALDH1A1SMN1; SMN2GRIN2B | |
| SCHEMBL31500735 | 0.71 | TYMS (0.36) | POLBMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL18152714 | 0.70 | ALDH1A1 (0.40) | RIPK1POLBMEN1HPGDKMT2A | |
| SCHEMBL18152622 | 0.68 | MGMT (0.39) | POLBMEN1KMT2ACYP1A2MAPT | |
| SCHEMBL18152810 | 0.68 | MDM2 (0.42) | POLBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9354810 | 0.68 | CALM1 (0.43) | RIPK1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3878066 | 0.67 | BCL2 (0.39) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10398538 | 0.66 | ALDH1A1 (0.44) | POLBMEN1HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |