Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | PKLR | P30613 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1352340 | 0.77 | PKM (0.77) | NPC1PKMPKLRRAB9AL3MBTL1 | |
| SCHEMBL6162105 | 0.77 | PARL (0.54) | MMP2HTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20042185 | 0.77 | MMP2 (0.65) | MMP2NPC1PKMPKLRRAB9A | |
| Hydrochloric Acid SCHEMBL3813273 | 0.76 | PARL (0.52) | MMP2HTTALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL3245890 | 0.76 | PKM (0.75) | NPC1PKMPKLRRAB9AL3MBTL1 | |
| SCHEMBL18162515 | 0.74 | MMP2 (0.70) | MMP2NPC1PKMPKLRRAB9A | |
| SCHEMBL20133743 | 0.74 | GAA (0.57) | L3MBTL1ALDH1A1MMP1MMP13SMN1; SMN2 | |
| SCHEMBL1665546 | 0.73 | ADRB1 (0.56) | NPC1PKMRAB9ASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL1584077 | 0.72 | ADRB1 (0.54) | NPC1PKMRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28704867 | 0.71 | KMT2A (0.53) | MMP2NPC1PKMPKLRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |