Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | GALR2 | O43603 | 4/20 | 0.57 |
| ▸ | GALR1 | P47211 | 2/20 | 0.57 |
| ▸ | GBA1 | P04062 | 12/20 | 0.56 |
| ▸ | BPTF | Q12830 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245932 | 0.87 | GALR2 (0.61) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL18153314 | 0.86 | LMNA (0.66) | MAPTGBA1BPTFLMNA | |
| SCHEMBL18162424 | 0.86 | GALR2 (0.55) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL18153367 | 0.85 | GALR2 (0.55) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL18153366 | 0.84 | MAPT (0.51) | MAPTGALR2GALR1BPTFLMNA | |
| SCHEMBL3240927 | 0.83 | GALR2 (0.77) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL18153312 | 0.82 | LMNA (0.49) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL3240588 | 0.82 | GALR2 (0.59) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL18153416 | 0.81 | CASP1 (0.61) | MAPTAPAF1GAAPPP1CASENP8 | |
| SCHEMBL3246321 | 0.81 | CASP1 (0.59) | MAPTAPAF1GAAPPP1CASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |