Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | BPTF | Q12830 | 1/20 | 0.45 |
| ▸ | GALR2 | O43603 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GALR1 | P47211 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153314 | 0.86 | LMNA (0.66) | LMNAMAPTCCNE1CDK2BPTF | |
| SCHEMBL18162512 | 0.86 | ACHE (0.46) | LMNAMAPTCCNE1CDK2BPTF | |
| SCHEMBL3246394 | 0.85 | MAPT (0.57) | LMNAMAPTCCNE1CDK2GALR2 | |
| SCHEMBL18153366 | 0.84 | MAPT (0.51) | LMNAMAPTCCNE1CDK2BPTF | |
| SCHEMBL18153311 | 0.82 | MAPT (0.58) | LMNAMAPTBPTFGALR2GALR1 | |
| SCHEMBL3240269 | 0.82 | LMNA (0.52) | LMNAMAPTCCNE1CDK2GALR2 | |
| SCHEMBL18162511 | 0.81 | LMNA (0.53) | LMNAMAPTCCNE1CDK2BPTF | |
| SCHEMBL3242837 | 0.81 | PKM (0.48) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3244303 | 0.80 | LMNA (0.49) | LMNAMAPTCCNE1CDK2GALR2 | |
| SCHEMBL8253256 | 0.80 | LMNA (0.52) | LMNAMAPTGALR2HSD17B10GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |