Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680354 | 0.81 | LMNA (0.62) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL11531290 | 0.79 | LMNA (0.51) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL1800595 | 0.78 | CA1 (0.56) | LMNAALDH1A1PKMMAPTHPGD | |
| SCHEMBL3680356 | 0.78 | LMNA (0.67) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL17915420 | 0.76 | S100A4 (0.57) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL7274704 | 0.76 | MAPT (0.46) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL1457741 | 0.75 | LMNA (0.58) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL12490543 | 0.75 | CA1 (0.58) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL28007961 | 0.75 | NQO1 (0.61) | LMNAALDH1A1HTTPKMMAPT | |
| SCHEMBL2017838 | 0.74 | LMNA (0.67) | LMNAALDH1A1HTTPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| WO-2016168467-A2 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | OGG1, UNG, AP2B1 | LMNA 354/4885ALDH1A1 3035/4885HTT 4083/4885 |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | OGG1, UNG, AP2B1 | LMNA 354/4885ALDH1A1 3035/4885HTT 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.