Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.74 |
| ▸ | MIF | P14174 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.62 |
| ▸ | STS | P08842 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31695377 | 1.00 | ESR2 (0.74) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL27085608 | 0.92 | ESR2 (0.69) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL27736901 | 0.86 | MIF (0.65) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL2166723 | 0.85 | ESR2 (1.00) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL27085595 | 0.84 | XDH (0.71) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL7117138 | 0.82 | MAOB (0.69) | ESR2RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL14879967 | 0.81 | XDH (0.74) | MIFMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27085612 | 0.81 | MIF (0.65) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL30023180 | 0.80 | MIF (1.00) | ESR2MIFMEN1KMT2ARAB9A | |
| SCHEMBL3281919 | 0.80 | MAOB (0.80) | RAB9AALDH1A1KDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313532-A1 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE | 2025-10-09 | — | — | US | disclosed |
| EP-4532016-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | University of Maryland, Baltimore (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |
| US-10718028-B2 | Fluorescent probes for abasic site detection | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-10718028-B2 | Fluorescent probes for abasic site detection | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| WO-2016168467-A2 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY (US) | 2016-10-20 | — | — | WO | disclosed |
| US-9085587-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | OGG1, UNG, AP2B1 | ESR2 2087/4885MIF 4821/4885MEN1 4876/4885 |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | OGG1, UNG, AP2B1 | ESR2 2087/4885MIF 4821/4885MEN1 4876/4885 |
| US-20250313532-A1 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | ADH1A, ALDH1A1, ADH1C | ESR2 711/4885MIF 2472/4885MEN1 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.