Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461557 | 0.88 | ACHE (0.42) | ACHETDP1ENPP3ENPP1RAB9A | |
| SCHEMBL9523363 | 0.85 | ACHE (0.41) | ACHERAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL195576 | 0.84 | LMNA (0.36) | ACHETDP1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27885932 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7950779 | 0.80 | ALDH1A1 (0.33) | ACHEALDH1A1 | |
| SCHEMBL7558439 | 0.77 | PTGS2 (0.37) | ACHERAPGEF4 | |
| SCHEMBL9982849 | 0.74 | ALDH1A1 (0.37) | ACHEALDH1A1RAPGEF4 | |
| SCHEMBL698699 | 0.73 | ACHE (0.42) | ACHETDP1ENPP3ENPP1RAB9A | |
| SCHEMBL29104461 | 0.73 | ACHE (0.36) | ACHETDP1ENPP3ENPP1RAB9A | |
| SCHEMBL7914615 | 0.71 | LMNA (0.41) | ACHETDP1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493906-A1 | HETEROLEPTIC CARBENE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051404-A1 | HETEROLEPTIC CARBENE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2011-05-05 | — | — | WO | disclosed |
| US-4072027-A | FLUOROCARBON REFRIGERANT, ASSYMETRICAL FURAN DERIVATIVE AS ABSORBENT | ALLIED CHEMICAL CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |