SCHEMBL195576

SCHEMBL195576

Cc1[c]c(-c2ccccc2)cc(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
TSHR P16473 2/20 0.36
ALOX12 P18054 1/20 0.36
ACHE P22303 1/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
PSMB5 P28074 2/20 0.33
HTT P42858 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
METAP2 P50579 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914615 0.89 LMNA (0.41) LMNATSHRALOX12ACHEKDM4E
SCHEMBL1815469 0.84 ACHE (0.36) LMNAACHEKDM4EALDH1A1SMN1; SMN2
SCHEMBL14635117 0.83 ALDH1A1 (0.39) LMNAKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL27885932 0.79 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL9523363 0.79 ACHE (0.41) LMNAACHEKDM4EALDH1A1MAPT
SCHEMBL7950779 0.78 ALDH1A1 (0.33) TSHRACHEALDH1A1
SCHEMBL723358 0.77 ALDH1A1 (0.36) LMNATSHRALOX12ACHEKDM4E
SCHEMBL4457527 0.76 KDM4E (0.33) LMNATSHRALOX12ACHEKDM4E
SCHEMBL4648563 0.76 KDM4E (0.33) LMNATSHRALOX12ACHEKDM4E
Benzene SCHEMBL8022186 0.75 ACHE (0.37) LMNATSHRALOX12ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9757811-B2 Method for treating surface of aluminum heat exchanger NIPPON PAINT SURF CHEMICALS CO., LTD. (JP) 2017-09-12 US claimed
US-20140223740-A1 METHOD FOR TREATING SURFACE OF ALUMINUM HEAT EXCHANGER NIPPON PAINT CO., LTD. (JP) 2014-08-14 US claimed
US-7550760-B2 Polyacenes and electronic devices generated therefrom XEROX CORPORATION (US) 2009-06-23 US claimed
US-20080146776-A1 Thiophene electronic devices XEROX CORPORATION 2008-06-19 US claimed
US-20070260069-A1 Functionalized heteroacenes XEROX CORPORATION 2007-11-08 US claimed
US-20070252138-A1 Polyacenes and electronic devices generated therefrom XEROX CORPORATION 2007-11-01 US claimed
EP-3626781-B1 FLUOROALKYL GROUP-CONTAINING CURABLE ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, AND TRANSDUCER OR THE LIKE PROVIDED WITH CURED PRODUCT DOW TORAY CO LTD (JP) 2024-06-26 EP disclosed
CN-107353233-B Method for catalytic synthesis of asymmetric azoxybenzene compound 温州大学 2023-02-24 CN disclosed
US-11479670-B2 Fluoroalkyl group-containing curable organopolysiloxane composition, cured product thereof, and transducer or the like provided with cured product DOW TORAY CO., LTD. (JP) 2022-10-25 US disclosed
US-20220017701-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, AND TRANSDUCER AND THE LIKE EQUIPPED WITH SAID CURED PRODUCT DOW TORAY CO., LTD. (JP) 2022-01-20 US disclosed
EP-3892686-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, AND TRANSDUCER AND THE LIKE EQUIPPED WITH SAID CURED PRODUCT Dow Toray Co., Ltd. (JP) 2021-10-13 EP disclosed
WO-2020116440-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, AND TRANSDUCER AND THE LIKE EQUIPPED WITH SAID CURED PRODUCT ダウ・東レ株式会社 2020-06-11 WO disclosed
EP-3626781-A1 FLUOROALKYL GROUP-CONTAINING CURABLE ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, AND TRANSDUCER OR THE LIKE PROVIDED WITH CURED PRODUCT Dow Toray Co., Ltd. (JP) 2020-03-25 EP disclosed
US-20070235720-A1 Polydiazaacenes and electronic devices generated therefrom XEROX CORPORATION 2007-10-11 US disclosed
US-20060235116-A1 Highly compatible and non-migratory polymeric uv-absorber CIBA SPECIALTY CHEMICALS CORP. 2006-10-19 US disclosed
US-20050059758-A1 Transparent polymer articles of low thickness LEPPARD DAVID GEORGE (CH) 2005-03-17 US disclosed
US-6626990-B2 Using aromatic- or heteraromatic-compounds having at least one hydroxyl or keto group bonded to the ring, with the oxidation of corresponding dihydroquinacridone salts CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-30 US disclosed
EP-0206219-B1 PHOTOSTABILISING OF SYDNONIMINES CASSELLA Aktiengesellschaft (DE) 1989-09-06 EP disclosed
EP-0206219-A1 Photostabilising of sydnonimines CASSELLA Aktiengesellschaft (DE) 1986-12-30 EP disclosed
EP-0059356-B1 SUBSTITUTED 3-AMINO-SYDNONIMINE, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION CASSELLA Aktiengesellschaft (DE) 1985-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070260069-A1 Functionalized heteroacenes SOD1, AHR, NR0B2 LMNA 3010/4885TSHR 157/4885ALOX12 1586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.