Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL30288558 | 0.88 | LDHA (0.47) | ALDH1A1ALOX15GABRPGABRDGABRA1 | |
| Acetoacetic Acid SCHEMBL8843224 | 0.84 | ALDH1A1 (0.38) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| Acetoacetic Acid SCHEMBL6572214 | 0.84 | ALDH1A1 (0.38) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| Acetic Acid SCHEMBL7950964 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALOX15GABRPGABRDGABRA1 | |
| Acetoacetic Acid SCHEMBL28466057 | 0.83 | ALDH1A1 (0.36) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| Acetoacetic Acid SCHEMBL2705262 | 0.81 | KDM4E (0.41) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| Acetoacetic Acid SCHEMBL2701583 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EKDM6BKDM5CEGLN1 | |
| Acetoacetic Acid SCHEMBL711498 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EKDM6BKDM5CEGLN1 | |
| Acetoacetic Acid SCHEMBL9278066 | 0.80 | KDM4E (0.48) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| Bicarbonate SCHEMBL18224038 | 0.80 | ALDH1A1 (0.48) | ALDH1A1ALOX15GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380538-A1 | AMINE FOR CURABLE POLYMER COMPOSITIONS WITH HIGH PROCESS RELIABILITY | Sika Technology AG (CH) | 2018-10-03 | — | — | EP | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| EP-3283550-A1 | AMIDINE-GROUP CONTAINING CATALYST | Sika Technology AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2017089472-A1 | AMINE FOR CURABLE POLYMER COMPOSITIONS WITH HIGH PROCESS RELIABILITY | SIKA TECHNOLOGY AG (CH) | 2017-06-01 | — | — | WO | disclosed |
| WO-2016180840-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016166336-A1 | AMIDINE-GROUP CONTAINING CATALYST | SIKA TECHNOLOGY AG (CH) | 2016-10-20 | — | — | WO | disclosed |