Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21234359 | 0.84 | ALDH1A1 (0.35) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL1562639 | 0.82 | LMNA (0.34) | KDM4EALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL1562641 | 0.82 | LMNA (0.34) | KDM4EALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL15274457 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL10067023 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL16984086 | 0.78 | SMN1; SMN2 (0.39) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL16984323 | 0.77 | SMN1; SMN2 (0.36) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL15277094 | 0.77 | ALOX15 (0.43) | KDM4EALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL10067022 | 0.74 | MGAM (0.36) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL24981904 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202965-A1 | RADIOTRACER COMPOSITIONS AND METHODS | GE HEALTHCARE LTD (GB) | 2022-06-30 | — | — | US | disclosed |
| US-11311636-B2 | Radiotracer compositions and methods | GE HEALTHCARE LIMITED (GB) | 2022-04-26 | — | — | US | disclosed |
| US-20210330824-A1 | PURIFICATION METHOD AND COMPOSITIONS | GE HEALTHCARE LTD (GB) | 2021-10-28 | — | — | US | disclosed |
| US-20190275182-A1 | RADIOTRACER COMPOSITIONS AND METHODS | GE HEALTHCARE LIMITED (GB) | 2019-09-12 | — | — | US | disclosed |
| US-10300156-B2 | Radiotracer compositions and methods | GE HEALTHCARE LIMITED (GB) | 2019-05-28 | — | — | US | disclosed |
| US-20160303262-A1 | PURIFICATION METHOD AND COMPOSITIONS | GE HEALTHCARE LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| US-20160303263-A1 | RADIOTRACER COMPOSITIONS AND METHODS | GE HEALTHCARE LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190275182-A1 | RADIOTRACER COMPOSITIONS AND METHODS | MET, METTL14, MEN1 | KDM4E 2261/4885ALDH1A1 4112/4885LMNA 3537/4885 |
| US-20160303263-A1 | RADIOTRACER COMPOSITIONS AND METHODS | MET, METTL14, MEN1 | KDM4E 2261/4885ALDH1A1 4112/4885LMNA 3537/4885 |
| US-20210330824-A1 | PURIFICATION METHOD AND COMPOSITIONS | FOLH1, ANPEP, PAICS | KDM4E 1334/4885ALDH1A1 2157/4885LMNA 2100/4885 |
| US-20220202965-A1 | RADIOTRACER COMPOSITIONS AND METHODS | MET, METTL14, MEN1 | KDM4E 2261/4885ALDH1A1 4112/4885LMNA 3537/4885 |
| US-10300156-B2 | Radiotracer compositions and methods | MET, METTL14, MEN1 | KDM4E 2261/4885ALDH1A1 4112/4885LMNA 3537/4885 |
| US-11311636-B2 | Radiotracer compositions and methods | MET, METTL14, MEN1 | KDM4E 2261/4885ALDH1A1 4112/4885LMNA 3537/4885 |
| US-20160303262-A1 | PURIFICATION METHOD AND COMPOSITIONS | FOLH1, ANPEP, PAICS | KDM4E 1334/4885ALDH1A1 2157/4885LMNA 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.