Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18157768 | 0.79 | KDM4E (0.42) | ALKGRM4CYP11B1CYP11B2KDM4E | |
| SCHEMBL18157770 | 0.79 | ALK (0.51) | ALKGRM4CYP11B1CYP11B2KDM4E | |
| SCHEMBL57903 | 0.68 | MEN1 (0.56) | GRM4CYP11B1CYP11B2KDM4ENFE2L2 | |
| SCHEMBL57902 | 0.68 | MEN1 (0.56) | GRM4CYP11B1CYP11B2KDM4ENFE2L2 | |
| SCHEMBL18157755 | 0.66 | NPC1 (0.50) | ALKKDM4ENFE2L2MEN1KMT2A | |
| SCHEMBL28555372 | 0.66 | NPC1 (0.50) | ALKKDM4ENFE2L2MEN1KMT2A | |
| SCHEMBL10719653 | 0.65 | GRM4 (0.50) | GRM4CYP11B1CYP11B2KDM4EMEN1 | |
| Toluene SCHEMBL6858981 | 0.65 | GRM4 (0.49) | GRM4CYP11B1CYP11B2KDM4EMEN1 | |
| Toluene SCHEMBL6858984 | 0.65 | GRM4 (0.49) | GRM4CYP11B1CYP11B2KDM4EMEN1 | |
| SCHEMBL1102800 | 0.65 | KDM4E (0.54) | ALKGRM4CYP11B1CYP11B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239834-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| WO-2016172193-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239834-B2 | Antibiotic sensitivity-restoring and photosensitive agents | XPA, PPOX, ALAD | ALK 4816/4885GRM4 4141/4885CYP11B1 4651/4885 |
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | ALK 4816/4885GRM4 4141/4885CYP11B1 4651/4885 |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | ALK 4816/4885GRM4 4141/4885CYP11B1 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.