SCHEMBL18157934

SCHEMBL18157934

CCCCC(CC)C(=O)N(Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.44
CYP1A2 P05177 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CTSK P43235 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
POLB P06746 1/20 0.40
LIN28A Q9H9Z2 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16899931 0.77 CYP1A2 (0.54) TRPM8CYP1A2L3MBTL1KMT2AMAPT
SCHEMBL10352587 0.76 TSHR (0.57) CYP1A2KMT2AMAPTSMN1; SMN2MEN1
SCHEMBL2189143 0.74 TRPM8 (0.47) TRPM8CYP1A2L3MBTL1MAPTSMN1; SMN2
SCHEMBL10290337 0.73 PGR (0.47) MAPTSMN1; SMN2ALDH1A1MAPK1HPGD
SCHEMBL17887964 0.72 MAPT (0.47) TRPM8CYP1A2MAPTSMN1; SMN2ALDH1A1
SCHEMBL12204158 0.72 TRPM8 (0.60) TRPM8CYP1A2L3MBTL1KMT2AMAPT
SCHEMBL10290433 0.72 HPGD (0.55) CYP1A2KMT2AMAPTSMN1; SMN2MEN1
SCHEMBL2187238 0.72 L3MBTL1 (0.55) TRPM8CYP1A2L3MBTL1KMT2AMAPT
SCHEMBL1066436 0.71 MAPT (0.50) TRPM8CYP1A2L3MBTL1KMT2AMAPT
SCHEMBL6170953 0.71 TRPM8 (0.59) TRPM8CYP1A2L3MBTL1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10989846-B2 Near infrared absorbing composition, near infrared cut filter, method of manufacturing near infrared cut filter, solid image pickup element, camera module, and image display device FUJIFILM CORPORATION (JP) 2021-04-27 US disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-20180188428-A1 NEAR-INFRARED CUT FILTER, METHOD FOR PRODUCING NEAR-INFRARED CUT FILTER, AND SOLID-STATE IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2018-07-05 US disclosed
US-20180175090-A1 NEAR INFRARED ABSORBING COMPOSITION, FILM, NEAR INFRARED CUT FILTER, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2018-06-21 US disclosed
US-9958576-B2 Near infrared ray absorbent composition, near infrared ray cut filter, manufacturing method of near infrared ray cut filter, solid image pickup element, camera module FUJIFILM CORPORATION (JP) 2018-05-01 US disclosed
US-9958576-B2 Near infrared ray absorbent composition, near infrared ray cut filter, manufacturing method of near infrared ray cut filter, solid image pickup element, camera module FUJIFILM CORPORATION (JP) 2018-05-01 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170102483-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, MANUFACTURING METHOD OF NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-04-13 US disclosed
US-20170102483-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, MANUFACTURING METHOD OF NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-04-13 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 TRPM8 1184/4885CYP1A2 3189/4885L3MBTL1 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.