Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | CD38 | P28907 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017788 | 0.84 | NT5E (0.59) | NPC1RAB9ASMN1; SMN2CSF1RFLT3 | |
| SCHEMBL15691400 | 0.84 | KDR (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1CSF1R | |
| SCHEMBL18146523 | 0.82 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL26074412 | 0.80 | ALDH1A1 (0.57) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL26074273 | 0.80 | GRM4 (0.57) | NPC1RAB9ASMN1; SMN2CSF1RFLT3 | |
| SCHEMBL21096059 | 0.78 | SMN1; SMN2 (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14082326 | 0.78 | PTPN1 (0.64) | NPC1RAB9ASMN1; SMN2TP53RXFP1 | |
| SCHEMBL30686047 | 0.78 | GRM4 (0.65) | NPC1RAB9ASMN1; SMN2GAAKDR | |
| SCHEMBL10415452 | 0.78 | GRM4 (0.65) | NPC1RAB9ASMN1; SMN2GAAKDR | |
| SCHEMBL18147607 | 0.77 | PYGL (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-11-30 | — | — | US | disclosed |
| US-9781935-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | NPC1 3361/4885RAB9A 567/4885SMN1; SMN2 3645/4885 |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | NPC1 3361/4885RAB9A 567/4885SMN1; SMN2 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.