Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244003 | 0.86 | P2RX3 (0.47) | P2RX3P2RX2HPGDSLMNATP53 | |
| SCHEMBL18166365 | 0.83 | P2RX3 (0.37) | P2RX3P2RX2HPGDSLMNATP53 | |
| SCHEMBL18166413 | 0.83 | P2RX3 (0.41) | P2RX3P2RX2LMNATP53HSP90AA1 | |
| SCHEMBL18166336 | 0.82 | P2RX3 (0.40) | P2RX3P2RX2MAPTHTT | |
| SCHEMBL18166430 | 0.82 | ADORA2A (0.41) | P2RX3P2RX2LMNAEPHX1 | |
| SCHEMBL18166368 | 0.82 | P2RX3 (0.47) | P2RX3P2RX2HPGDSEPHX1 | |
| SCHEMBL18166343 | 0.82 | P2RX3 (0.38) | P2RX3P2RX2LMNATP53HSP90AA1 | |
| SCHEMBL18036448 | 0.82 | P2RX3 (0.35) | P2RX3P2RX2LMNATP53HSP90AA1 | |
| SCHEMBL18166384 | 0.81 | P2RX3 (0.36) | P2RX3P2RX2EPHX1 | |
| SCHEMBL18166376 | 0.81 | P2RX3 (0.39) | P2RX3P2RX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |