Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166369 | 0.94 | P2RX3 (0.38) | P2RX3P2RX2CTSANPC1RAB9A | |
| SCHEMBL18166360 | 0.89 | CTSA (0.33) | CTSANPC1RAB9AMAPTPOLB | |
| SCHEMBL10243628 | 0.88 | P2RX3 (0.46) | P2RX3P2RX2CTSANPC1RAB9A | |
| SCHEMBL18166387 | 0.86 | TP53 (0.39) | CTSANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL18166412 | 0.86 | P2RX3 (0.50) | P2RX3P2RX2WDR5 | |
| SCHEMBL18166339 | 0.85 | P2RX3 (0.48) | P2RX3P2RX2CTSANPC1RAB9A | |
| SCHEMBL18036416 | 0.85 | DGAT2 (0.34) | P2RX3P2RX2MAPTPTGS2 | |
| SCHEMBL18036396 | 0.84 | DGAT2 (0.37) | P2RX3P2RX2CTSAMAPTPTGS2 | |
| SCHEMBL10244060 | 0.82 | P2RX3 (0.51) | P2RX3P2RX2NPC1RAB9AWDR5 | |
| SCHEMBL18166270 | 0.80 | P2RX3 (0.55) | P2RX3P2RX2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |