Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166343 | 0.94 | P2RX3 (0.38) | P2RX3P2RX2HPGDMAPTLMNA | |
| SCHEMBL18166365 | 0.91 | P2RX3 (0.37) | P2RX3P2RX2HPGDMAPTKMT2A | |
| SCHEMBL10244802 | 0.87 | P2RX3 (0.47) | P2RX3P2RX2HPGDCYP2C9CYP1A2 | |
| SCHEMBL18036448 | 0.81 | P2RX3 (0.35) | P2RX3P2RX2HPGDMAPTMEN1 | |
| SCHEMBL18166413 | 0.81 | P2RX3 (0.41) | P2RX3P2RX2HPGDMAPTALDH1A1 | |
| SCHEMBL18166320 | 0.81 | P2RX3 (0.37) | P2RX3P2RX2HPGDMAPTLMNA | |
| SCHEMBL18166336 | 0.80 | P2RX3 (0.40) | P2RX3P2RX2MAPTKDM4EHTT | |
| SCHEMBL18166368 | 0.80 | P2RX3 (0.47) | P2RX3P2RX2MEN1KMT2A | |
| SCHEMBL18166430 | 0.80 | ADORA2A (0.41) | P2RX3P2RX2LMNA | |
| SCHEMBL18166376 | 0.79 | P2RX3 (0.39) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |