Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166274 | 0.88 | P2RX3 (0.49) | FAAHP2RX3P2RX2 | |
| SCHEMBL10244650 | 0.88 | P2RX3 (0.48) | MAOBPKMMAPTRAB9ANPC1 | |
| SCHEMBL18166455 | 0.87 | FAAH (0.42) | FAAHSMN1; SMN2 | |
| SCHEMBL18166296 | 0.85 | EPHX1 (0.45) | PKMFAAHMAPTRAB9ANPC1 | |
| SCHEMBL18166269 | 0.85 | P2RX3 (0.38) | PKMSMN1; SMN2P2RX3P2RX2 | |
| SCHEMBL18166390 | 0.82 | P2RX3 (0.50) | FAAHP2RX3P2RX2 | |
| SCHEMBL18036393 | 0.81 | P2RX3 (0.43) | FAAHP2RX3P2RX2 | |
| SCHEMBL18166287 | 0.81 | P2RX3 (0.47) | FAAHP2RX3P2RX2 | |
| SCHEMBL18166281 | 0.80 | P2RX3 (0.41) | FAAHP2RX3P2RX2 | |
| SCHEMBL18036425 | 0.80 | P2RX3 (0.35) | FAAHP2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |