SCHEMBL18167012

SCHEMBL18167012

COC(=O)C(C)CN1CCN(C)CC1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
TP53 P04637 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP2D6 P10635 2/20 0.41
USP2 O75604 1/20 0.40
MC4R P32245 2/20 0.40
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
PIK3CD O00329 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12285113 0.85 KDM4E (0.40) SMN1; SMN2MAPTALDH1A1CYP2D6MC4R
SCHEMBL64561 0.85 CHRM2 (0.46) POLBSMN1; SMN2MAPTALDH1A1CYP2D6
SCHEMBL23886458 0.85 CHRM2 (0.42) POLBSMN1; SMN2ALDH1A1CYP2D6PIK3CD
SCHEMBL16266010 0.84 ALDH1A1 (0.40) POLBTP53SMN1; SMN2TSHRALDH1A1
SCHEMBL9774559 0.83 CHRM2 (0.49) POLBMAPTTSHRALDH1A1CYP2D6
SCHEMBL16267241 0.80 PADI1 (0.55) POLBSMN1; SMN2ALDH1A1CYP2D6KDM4E
SCHEMBL12251157 0.80 PADI1 (0.55) POLBSMN1; SMN2ALDH1A1CYP2D6KDM4E
SCHEMBL1816293 0.80 ALDH1A1 (0.64) SMN1; SMN2MAPTTSHRALDH1A1USP2
SCHEMBL16265832 0.80 ALDH1A1 (0.36) POLBSMN1; SMN2ALDH1A1CYP2D6MC4R
SCHEMBL16265733 0.78 ALDH1A1 (0.35) POLBTSHRALDH1A1CYP2D6PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3084152-B1 FLUORINATED OLEFINS AS WORKING FLUIDS AND METHODS OF USING SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-05-31 EP disclosed
US-10557069-B2 Fluorinated olefins as working fluids and methods of using same 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-02-11 US disclosed
US-10364360-B2 Surface coating material, coating film, and hydrophilic oil repellent member MITSUBISHI MATERIALS CORPORATION (JP) 2019-07-30 US disclosed
US-20190225852-A1 FLUORINATED OLEFINS AS WORKING FLUIDS AND METHODS OF USING SAME 3M INNOVATIVE PROPERTIES CO (US) 2019-07-25 US disclosed
US-10280351-B2 Fluorinated olefins as working fluids and methods of using same 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-05-07 US disclosed
US-10208210-B2 Hydrophilic oil repellent and production method of same, surface coating material, coating film, resin composition, oil-water separation filter material, and porous body MITSUBISHI MATERIALS CORPORATION (JP) 2019-02-19 US disclosed
US-20180320040-A1 FLUORINATED OLEFINS AS WORKING FLUIDS AND METHODS OF USING SAME 3M INNOVATIVE PROPERTIES COMPANY 2018-11-08 US disclosed
US-9957428-B2 Fluorinated olefins as working fluids and methods of using same 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-05-01 US disclosed
US-20170210912-A1 HYDROPHILIC OIL REPELLENT AND PRODUCTION METHOD OF SAME, SURFACE COATING MATERIAL, COATING FILM, RESIN COMPOSITION, OIL-WATER SEPARATION FILTER MATERIAL, AND POROUS BODY MITSUBISHI MATERIALS ELECTRONIC CHEMICALS CO., LTD. (JP) 2017-07-27 US disclosed
US-20170210916-A1 SURFACE COATING MATERIAL, COATING FILM, AND HYDROPHILIC OIL REPELLENT MEMBER MITSUBISHI MATERIALS CORPORATION (JP) 2017-07-27 US disclosed
EP-3176236-A1 SURFACE-COATING MATERIAL, COATED FILM, AND HYDROPHILIC/OIL-REPELLENT MATERIAL Mitsubishi Materials Corporation (JP) 2017-06-07 EP disclosed
EP-3176237-A1 HYDROPHILIC OIL REPELLENT AGENT AND METHOD FOR MANUFACTURING SAME, AND SURFACE COVERING MATERIAL, COATING FILM, RESIN COMPOSITION, OIL-WATER SEPARATION FILTER MEDIUM, AND POROUS BODY Mitsubishi Materials Corporation (JP) 2017-06-07 EP disclosed
US-20160312096-A1 FLUORINATED OLEFINS AS WORKING FLUIDS AND METHODS OF USING SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-10-27 US disclosed
EP-3084152-A1 FLUORINATED OLEFINS AS WORKING FLUIDS AND METHODS OF USING SAME 3M Innovative Properties Company (US) 2016-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210912-A1 HYDROPHILIC OIL REPELLENT AND PRODUCTION METHOD OF SAME, SURFACE COATING MATERIAL, COATING FILM, RESIN COMPOSITION, OIL-WATER SEPARATION FILTER MATERIAL, AND POROUS BODY FABP4, FFAR1, FFAR2 POLB 3500/4885TP53 3080/4885SMN1; SMN2 3586/4885
US-10208210-B2 Hydrophilic oil repellent and production method of same, surface coating material, coating film, resin composition, oil-water separation filter material, and porous body FABP4, FFAR1, FFAR2 POLB 3500/4885TP53 3080/4885SMN1; SMN2 3586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.