SCHEMBL18169342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16809585	0.85	ALPG (0.46)	ALDH1A1SIGMAR1TSHRMEN1KMT2A
	SCHEMBL16809589	0.85	KCNE1 (0.42)	ALDH1A1TDP1SIGMAR1TSHRMEN1
	SCHEMBL16809481	0.78	ALPG (0.43)	ALDH1A1SIGMAR1MEN1KMT2AMAPT
	SCHEMBL19905593	0.77	HTR2B (0.39)	ALDH1A1HTR1AHTR2BSIGMAR1TSHR
	SCHEMBL16809431	0.75	HTR2B (0.41)	ALDH1A1TDP1HTR1AHTR2BSIGMAR1
	SCHEMBL16797756	0.74	HTR2B (0.42)	ALDH1A1TDP1HTR1AHTR2BSIGMAR1
	SCHEMBL16797753	0.73	HTR2B (0.41)	ALDH1A1TDP1HTR1AHTR2BSIGMAR1
	SCHEMBL18169360	0.72	SIGMAR1 (0.43)	ALDH1A1TDP1SIGMAR1TSHRMEN1
	SCHEMBL12967407	0.72	ALDH1A1 (0.47)	ALDH1A1TDP1HTR1AHTR2BSIGMAR1
	SCHEMBL16809708	0.72	ALPG (0.45)	ALDH1A1SIGMAR1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.