Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FGB | P02675 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | STK10 | O94804 | 15/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 15/20 | 0.52 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.48 |
| ▸ | WEE1 | P30291 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18170553 | 0.87 | RAB9A (0.47) | ADORA2AMEN1ALDH1A1FGBPOLB | |
| SCHEMBL18170943 | 0.74 | CASP3 (0.54) | MEN1POLBMAPTMAPK1RAB9A | |
| SCHEMBL28621084 | 0.73 | ALDH1A1 (0.48) | ADORA2AMEN1ALDH1A1FGBPOLB | |
| SCHEMBL7429649 | 0.73 | THRB (0.55) | ADORA2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL384815 | 0.73 | TOP1 (0.55) | MEN1ALDH1A1MAPTKMT2ASTK10 | |
| SCHEMBL18170525 | 0.73 | MAOA (0.45) | ADORA2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL29378366 | 0.73 | TOP1 (0.55) | MEN1ALDH1A1MAPTKMT2ASTK10 | |
| SCHEMBL11307123 | 0.72 | WEE1 (0.51) | ADORA2AMEN1ALDH1A1FGBPOLB | |
| SCHEMBL395260 | 0.72 | ALDH1A1 (0.67) | ADORA2AMEN1ALDH1A1FGBPOLB | |
| SCHEMBL6840031 | 0.71 | ALDH1A1 (0.57) | ADORA2AMEN1ALDH1A1FGBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311772-A1 | COMPOUNDS AS TNIK, IKKEPSILON AND TBK1 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2016-10-27 | — | — | US | claimed |
| US-9856216-B2 | Compounds as TNIK, IKKε and TBK1 inhibitors and pharmaceutical composition comprising same | GREEN CROSS CORPORATION (KR) | 2018-01-02 | — | — | US | disclosed |
| US-20160311772-A1 | COMPOUNDS AS TNIK, IKKEPSILON AND TBK1 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2016-10-27 | — | — | US | disclosed |
| US-20160311772-A1 | COMPOUNDS AS TNIK, IKKEPSILON AND TBK1 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311772-A1 | COMPOUNDS AS TNIK, IKKEPSILON AND TBK1 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | TNIK, TNK1, NFKBIA | ADORA2A 4268/4885MEN1 1064/4885ALDH1A1 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.