SCHEMBL1817189

SCHEMBL1817189

CC1CCCC(C(=O)O)=C1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
OAT P04181 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 1/20 0.34
RCE1 Q9Y256 1/20 0.34
HCAR2 Q8TDS4 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ABCC1 P33527 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866530 0.86 HCAR2 (0.39) KMT2ACA1CA2CA4HCAR2
SCHEMBL6659836 0.84 ALDH1A1 (0.33) KMT2ACA1CA2CA4NPC1
SCHEMBL22092595 0.83 SLC6A3 (0.40) NPC1RAB9AALDH1A1MAPTGAA
SCHEMBL22077234 0.83 SLC6A3 (0.40) NPC1RAB9AALDH1A1MAPTGAA
SCHEMBL8039515 0.82 GRM5 (0.33) KMT2ACA1CA2CA4NPC1
SCHEMBL5573551 0.81 KMT2A (0.43) KMT2ACA1CA2CA4NPC1
SCHEMBL1780513 0.81 KMT2A (0.43) KMT2ACA1CA2CA4NPC1
SCHEMBL23795651 0.78 NPC1 (0.38) KMT2ACA1CA2CA4NPC1
SCHEMBL19617275 0.78 NPC1 (0.38) KMT2ACA1CA2CA4NPC1
SCHEMBL5474955 0.77 KDM4E (0.39) GAAOATKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024068483-A1 LED-CURABLE OFFSET INKS CONTAINING ALUMINUM ADDITIVES SUN CHEMICAL B.V. (NL) 2024-04-04 WO claimed
CN-113881203-A Polylactic acid composition and preparation method and application thereof 联泓(江苏)新材料研究院有限公司 2022-01-04 CN claimed
US-4600521-A Electron-beam reactive magnetic coating composition for magnetic recording media NIPPON ZEON CO., LTD. (JP) 1986-07-15 US claimed
JP-2003404-A None JP disclosed
WO-2024068483-A1 LED-CURABLE OFFSET INKS CONTAINING ALUMINUM ADDITIVES SUN CHEMICAL B.V. (NL) 2024-04-04 WO disclosed
US-20230278988-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2023-09-07 US disclosed
US-20230278988-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2023-09-07 US disclosed
CN-116444498-A THR beta receptor agonist compound, preparation method and application thereof 拓臻股份有限公司 2023-07-18 CN disclosed
CN-113194958-B THR beta receptor agonist compound, preparation method and application thereof 拓臻股份有限公司 2023-05-23 CN disclosed
WO-2023027013-A1 RESIN COMPOSITION 味の素株式会社 2023-03-02 WO disclosed
WO-2022196696-A1 RESIN SHEET 味の素株式会社 2022-09-22 WO disclosed
EP-0540751-A1 STEROID COMPOUND COMBINED WITH POLYSACCHARIDE Eisai Co., Ltd. (JP) 1993-05-12 EP disclosed
EP-0161220-B1 PROCESS FOR THE PREPARATION OF BETA-(BENZOTHIAZOLYLTHIO) AND BETA (BENZIMIDAZOLYLTHIO)CARBOXYLIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1991-08-14 EP disclosed
JP-H023404-A PREPARATION OF AQUEOUS DISPERSION OF COPOLYMER MITSUBISHI YUKA BADISCHE CO LTD 1990-01-09 JP disclosed
EP-0259265-A1 3-Methyl phthalimides CIBA-GEIGY AG (CH) 1988-03-09 EP disclosed
US-4652653-A Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio)-carboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1987-03-24 US disclosed
US-4612378-A Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio-carboxylic acids CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
US-4600521-A Electron-beam reactive magnetic coating composition for magnetic recording media NIPPON ZEON CO., LTD. (JP) 1986-07-15 US disclosed
EP-0161220-A2 Process for the preparation of beta-(benzothiazolylthio) and beta (benzimidazolylthio)carboxylic-acid derivatives CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed
EP-0126030-A2 Process for the preparation of beta-(benzothiazolylthio) and beta-(benzimidazolylthio) carboxylic acids CIBA-GEIGY AG (CH) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278988-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, TRHR KMT2A 2197/4885CA1 4066/4885CA2 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.