SCHEMBL181734

SCHEMBL181734

O=C1NC(c2ccccc2)SC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.42
▸ HSD17B10 Q99714 3/20 0.42
▸ HPGD P15428 2/20 0.42
▸ TSHR P16473 2/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ CYP3A4 P08684 2/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ CA2 P00918 1/20 0.41
▸ KMT2A Q03164 4/20 0.40
▸ KDM4E B2RXH2 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ TNKS2 Q9H2K2 2/20 0.40
▸ MITF O75030 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ MDM2 Q00987 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ GALK1 P51570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015478 0.80 ALDH1A1 (0.40) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL11024958 0.73 CYP2C9 (0.41) ALDH1A1HSD17B10HPGDTSHRCYP2C9
SCHEMBL15669988 0.67 SMN1; SMN2 (0.54) ALDH1A1HSD17B10HPGDCYP1A2CYP3A4
SCHEMBL26419941 0.67 HSD17B10 (0.42) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL434104 0.67 IDO1 (0.53) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL5450446 0.65 SMN1; SMN2 (0.59) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL27329636 0.64 CA2 (0.43) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL18890738 0.64 HSD17B10 (0.40) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL14148596 0.64 HSD17B10 (0.40) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL19382255 0.62 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDTSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5064747-A Improved photosensitivity using an unsaturated 1,3-dithiol-2-ylidene derivative; lithographic printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 — — US claimed
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound FUJIFILM CORPORATION (JP) 2026-05-12 — — US disclosed
US-12568754-B2 Laminate comprising a wavelength-conversion material and a wavelength-selective absorption layer, display device, and organic electroluminescent display device FUJIFILM CORPORATION (JP) 2026-03-03 — — US disclosed
US-20250393473-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, AND OPTICAL SENSOR FUJIFILM CORP (JP) 2025-12-25 — — US disclosed
US-20250374741-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORP (JP) 2025-12-04 — — US disclosed
US-12484442-B2 Photoelectric conversion element, imaging element, optical sensor, and compound FUJIFILM CORPORATION (JP) 2025-11-25 — — US disclosed
US-12479989-B2 Wavelength selective absorption filter and organic electroluminescent display device FUJIFILM CORPORATION (JP) 2025-11-25 — — US disclosed
US-20250351722-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORP (JP) 2025-11-13 — — US disclosed
US-20250346750-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2025-11-13 — — US disclosed
EP-4633333-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, PHOTOSENSOR, METHOD FOR PRODUCING IMAGING DEVICE, AND COMPOUND FUJIFILM Corporation (JP) 2025-10-15 — — EP disclosed
US-4025349-A Silver halide photographic elements spectrally sensitized with an acetylenic analog of cyanine or merocyanine dyes EASTMAN KODAK COMPANY (US) 1977-05-24 — — US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 — — US disclosed
US-4007170-A SILVER HALIDE SENSITIZERS EASTMAN KODAK COMPANY (US) 1977-02-08 — — US disclosed
US-3985540-A Metal complexes of hydroxyquinoline and polymeric porous granules GAF CORPORATION (US) 1976-10-12 — — US disclosed
US-3976661-A SENSITIZERS, FILTERS EASTMAN KODAK COMPANY (US) 1976-08-24 — — US disclosed
US-3961952-A ELECTROPHOTOGRAPHY, SUPPORTS, COATINGS ITEK CORPORATION (US) 1976-06-08 — — US disclosed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 — — US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 — — US disclosed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 — — US disclosed
US-3935010-A IMIDAZOQUINOXALINE DESENSITIZER EASTMAN KODAK COMPANY (US) 1976-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250351722-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND EPB41L2, PDE6C, CRY1 ALDH1A1 2842/4885HSD17B10 4224/4885HPGD 3207/4885
US-12568754-B2 Laminate comprising a wavelength-conversion material and a wavelength-selective absorption layer, display device, and organic electroluminescent display device STRA6, CDH1, EPCAM ALDH1A1 395/4885HSD17B10 2999/4885HPGD 3248/4885
US-20250393473-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, AND OPTICAL SENSOR NR2E3, CRY1, CRY2 ALDH1A1 724/4885HSD17B10 1891/4885HPGD 4077/4885
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound SCO2, CRY2, PYM1 ALDH1A1 4528/4885HSD17B10 3613/4885HPGD 3900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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