Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.70 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.70 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058843 | 0.96 | MAPT (0.77) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL18127013 | 0.93 | MAPT (0.69) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16745699 | 0.90 | MAPT (0.66) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2285435 | 0.89 | MAPT (0.89) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16342038 | 0.89 | MAPT (0.64) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1644447 | 0.88 | MAPT (0.87) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5174468 | 0.88 | FTO (0.75) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL700722 | 0.87 | FTO (0.73) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL22434156 | 0.87 | FTO (0.73) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23083080 | 0.87 | FTO (0.73) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180092845-A1 | ENZYME-RESPONSIVE NANOPARTICLES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-04-05 | — | — | US | disclosed |
| WO-2016172386-A1 | ENZYME-RESPONSIVE NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-27 | — | — | WO | disclosed |
| CN-101451018-A | Yellow fluorochrome and synthetic method and use thereof | UNIV NORTHWESTERN (CN) | 2009-06-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092845-A1 | ENZYME-RESPONSIVE NANOPARTICLES | TNNI3, TNNT2, TNNC1 | MAPT 3432/4885MEN1 3170/4885KMT2A 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.