Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.73 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469741 | 0.87 | FTO (0.79) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6622095 | 0.87 | FTO (0.79) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL4663321 | 0.87 | FTO (0.82) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL18173525 | 0.87 | MAPT (0.71) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL7740798 | 0.86 | FTO (0.81) | FTOMAPTMEN1KMT2ATDP1 | |
| SCHEMBL18127013 | 0.86 | MAPT (0.69) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL5694330 | 0.86 | FTO (0.89) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL8648355 | 0.86 | FTO (0.94) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL16533 | 0.86 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL30272223 | 0.86 | FTO (1.00) | FTOMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175667-A1 | Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices | THE JOHNS HOPKINS UNIVERSITY | 2022-06-09 | — | — | US | disclosed |
| US-20210069375-A1 | Extracellular Matrices, Uses thereof, and Method for Making Extracellular Matrices | THE JOHNS HOPKINS UNIVERSITY | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069375-A1 | Extracellular Matrices, Uses thereof, and Method for Making Extracellular Matrices | MMP1, MATR3, COL1A1 | FTO 2910/4885MAPT 3975/4885MEN1 1470/4885 |
| US-20220175667-A1 | Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices | EPCAM, CD44, MATR3 | FTO 2394/4885MAPT 3664/4885MEN1 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.