Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 8/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627874 | 0.87 | L3MBTL1 (0.41) | L3MBTL1GGPS1 | |
| SCHEMBL18534183 | 0.87 | L3MBTL1 (0.41) | L3MBTL1GGPS1 | |
| SCHEMBL18534153 | 0.85 | MAPT (0.39) | L3MBTL1ALDH1A1MAPTNAMPTKMT2A | |
| SCHEMBL18534224 | 0.79 | EGLN3 (0.42) | L3MBTL1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL20845830 | 0.78 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTRAB9ANAMPT | |
| SCHEMBL18183254 | 0.75 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1PIK3CGLMNAHTT | |
| SCHEMBL17933331 | 0.75 | ACHE (0.38) | ALDH1A1 | |
| SCHEMBL17933369 | 0.72 | ACHE (0.36) | L3MBTL1 | |
| SCHEMBL24628384 | 0.71 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1LMNASMN1; SMN2JAK2 | |
| SCHEMBL16101449 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311838-A1 | PHOSPHOHISTIDINE MIMETICS AND ANTIBODIES TO SAME | PHPT1, CD4, HCLS1 | L3MBTL1 4199/4885ALDH1A1 4535/4885MAPT 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.